4-Epioxytetracycline

4-Epioxytetracycline Structure
4-Epioxytetracycline structure
Common Name 4-Epioxytetracycline
CAS Number 14206-58-7 Molecular Weight 460.43400
Density N/A Boiling Point 727.8ºC at 760mmHg
Molecular Formula C22H24N2O9 Melting Point 168ºC
MSDS N/A Flash Point 394ºC

Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds.

J. AOAC Int. 95(4) , 1010-5, (2012)

A selective and accurate LC/MS/MS method for the simultaneous determination of chlortetracycline (CTC), oxytetracycline (OTC), tetracycline (TC), and doxycycline (DC) in animal feeds was developed. Samples were extracted with Na2EDTA-McIlvaine buffer and furt...

Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

Angew. Chem. Int. Ed. Engl. 51(44) , 11136-40, (2012)

A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes and characterization of the resulting biosynthetic intermed...

Topical steroids for chronic wounds displaying abnormal inflammation.

Ann. R. Coll. Surg. Engl. 95(4) , 291-6, (2013)

Chronic, non-healing wounds are often characterised by an excessive, and detrimental, inflammatory response. We review our experience of using a combined topical steroid, antibiotic and antifungal preparation in the treatment of chronic wounds displaying abno...

The interaction of polysaccharide from Auricularia polytricha with quantum dots and the protection of plasmid DNA from damage.

Appl. Biochem. Biotechnol. 169(8) , 2263-72, (2013)

As a kind of folk medicine, edible mushrooms are known to be of medicinal characteristics, for example antitumor activity. However, the mechanism is not clear. In this study, the fluorescence (FL) spectroscopy was used to study the binding reactions of polysa...

Vascular malformation of the glans penis successfully treated with Nd:YAG laser.

Dermatol. Online J. 18(10) , 16, (2012)

Penile venous malformations are uncommon and those located on the glans are even rarer. Treatment of venous malformations of the glans is currently controversial. Neodynium (Nd):YAG laser treatment may be a useful option.

Antibacterial activity of the soil-bound antimicrobials oxytetracycline and ofloxacin.

Environ. Toxicol. Chem. 33(4) , 776-83, (2014)

Soil contamination of antimicrobials has become an increasing concern because of the potential risks to the soil microbial ecosystem and human health. The present study investigated sorption and desorption behaviors of oxytetracycline (OTC) and ofloxacin (OFL...

Occurrence of antibiotics and antibiotic resistances in soils from wastewater irrigation areas in Beijing and Tianjin, China.

Environ. Pollut. 193 , 94-101, (2014)

Non-irrigated and wastewater-irrigated soils were collected from five wastewater irrigation areas in Beijing and Tianjin, China. The concentrations of sulfadiazine, sulfamethoxazole, oxytetracycline and chlortetracycline in the soils were determined. Abundanc...

Acidification of non-medicated and oxytetracycline-medicated cattle manures during anaerobic digestion.

Environ. Technol. 35(17-20) , 2373-9, (2014)

Possible adverse effects of a commonly used veterinary antibiotic, oxytetracycline (OTC), on acidogenic phase of anaerobic digestion of cattle manure along with optimum operating conditions were investigated. A standard veterinary practice of 50 ml OTC soluti...

Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro.

Phytomedicine 20(5) , 432-5, (2013)

Epigallocatechin gallate (EGCG), the major catechin contained in tea leaves, is known to possess the synergistic anti-staphylococcal activity in combination with various β-lactam antibiotics and tetracycline. In the present study, we explored the in vitro com...

Preparation, characterization, and phenol adsorption of activated carbons from oxytetracycline bacterial residue.

J. Air Waste Manag. Assoc. 62(12) , 1394-402, (2012)

The oxytetracycline bacterial residue-activated carbon (OBR-AC) prepared from oxytetracycline bacterial residue with K2CO3 under chemical activation was studied. The effects of activation temperature, activation time, and activation ratio on the specific surf...