chloropyrimidine
chloropyrimidine structure
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Common Name | chloropyrimidine | ||
|---|---|---|---|---|
| CAS Number | 1722-12-9 | Molecular Weight | 114.533 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 199.2±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H3ClN2 | Melting Point | 63-66 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 109.2±4.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine.
J. Org. Chem. 74(8) , 3221-4, (2009) A cobalt-catalyzed cross-coupling of aryl halides with 2-chloropyrimidines or 2-chloropyrazines is reported in satisfactory to high yields. The key step of this procedure is the formation of aromatic organozinc reagents and their coupling with 2-chlorodiazine... |
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Ru-catalysed C-H arylation of indoles and pyrroles with boronic acids: scope and mechanistic studies.
Chemistry 21(14) , 5380-6, (2015) The Ru-catalysed C2-H arylation of indoles and pyrroles by using boronic acids under oxidative conditions is reported. This reaction can be applied to tryptophan derivatives and tolerates a wide range of functional groups on both coupling partners, including ... |
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Expedient parallel synthesis of 2-amino-4-heteroarylpyrimidines.
Org. Lett. 7(19) , 4113-6, (2005) [reaction: see text] An expedient synthesis of diverse 2-amino-4-heteroarylpyrimidines via a 2-chloropyrimidine intermediate is described. A series of potentially biologically active analogues have been synthesized in two parallel steps to afford focused arra... |
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Synthesis and spectral characterization of new bis(2-(pyrimidin-2-yl)ethoxy)alkanes and their pharmacological activity.
Arch. Pharm. (Weinheim) 345(8) , 663-9, (2012) The pyrimidine nucleus is an important component of nucleic acids (DNA and RNA) and vitamins (B(2) and folic acid). It is evident from the literature that pyrimidine derivatives possess a wide spectrum of biological activities such as antioxidant, anticancer,... |
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Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding.
Chem. Cent. J. 5 , 72, (2011) Fluorescent dyes with biocompatible functional group and good fluorescence behavior are used as biosensor for monitoring different biological processes as well as detection of protein assay. All reported fluorophore used as sensors are having high selectivity... |
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Unexpected rearrangement of enantiomerically pure 3-aminoquinuclidine as a simple way of preparing diastereomeric octahydropyrrolo[2,3-c]pyridine derivatives.
Chirality 21(7) , 681-91, (2009) Reaction of (S)- or (R)-3-aminoquinuclidine with 2-chloropyrimidine or 2-bromopyrimidine led to an unexpected formation of both cis- and trans-octahydropyrrolo [2,3]pyridine derivatives. A single-step synthesis of two of the four stereoisomers of these octahy... |