arsenic trichloride
arsenic trichloride structure
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Common Name | arsenic trichloride | ||
|---|---|---|---|---|
| CAS Number | 7784-34-1 | Molecular Weight | 181.28100 | |
| Density | 2.163 | Boiling Point | 130.2ºC(lit.) | |
| Molecular Formula | AsCl3 | Melting Point | -16ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 130.2ºC | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Remediation of mercury contaminated saltwater with functionalized silica coated magnetite nanoparticles.
Sci. Total Environ. 557-558 , 712-21, (2016) The study aimed to evaluate the efficiency of dithiocarbamate functionalized silica coated magnetite nanoparticles (NPs) for Hg decontamination of saltwater either contaminated with Hg alone or with As and Cd. For this, the residual levels of Hg in seawater w... |
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Synthesis and identification of [76As]arsenic trichloride.
Int. J. Rad. Appl. Instrum. A. 37(6) , 545-7, (1986) Radiosynthesis of arsenic trichloride (AsCl3) was achieved using 76As as the radionuclide of choice for preliminary investigations. The synthesis required neutron activation of arsenic trioxide (As2O3) followed by reaction with sulfur monochloride (S2Cl2) und... |
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[Anti-apoptosis effect of VEGF on the human chronic myelocytic leukemia cell line K562].
Zhongguo Shi Yan Xue Ye Xue Za Zhi 13(5) , 778-82, (2005) To explore the effects of vascular endothelial growth factor (VEGF) on the mechanisms of CML pathogenesis, the effect of VEGF on K562 cell apoptosis induced by As(2)O(3) was analyzed through morphologic observation, DNA fragmentation agarose gel electrophores... |
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Mechanism of action of all-trans retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia.
Gan To Kagaku Ryoho. 29 Suppl 1 , 214-8, (2002) Treatment of APL with ATRA or As2O3 alone or in combination with chemotherapy yields a complete remission as high as 85%-95%, but their mechanisms of action remain unclear. The mechanisms of action underlying ATRA treatment are (1) relocalization of the PML r... |
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Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria.
Cancer Res. 64(24) , 8960-7, (2004) Although mechanisms of arsenic trioxide (As(2)O(3))-induced cell death have been studied extensively in hematologic cancers, those in solid cancers have yet to be clearly defined. In this study, we showed that the translocation of apoptosis-inducing factor (A... |
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Nucleolin links to arsenic-induced stabilization of GADD45alpha mRNA.
Nucleic Acids Res. 34(2) , 485-95, (2006) The present study shows that arsenic induces GADD45alpha (growth arrest and DNA damage inducible gene 45alpha) mainly through post-transcriptional mechanism. Treatment of the human bronchial epithelial cell line, BEAS-2B, with arsenic(III) chloride (As3+) res... |
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Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.
J. Pharmacol. Exp. Ther. 332(1) , 66-75, (2010) Arsenic activates nuclear factor erythroid 2-related factor 2 (Nrf2) to induce phase II and antioxidative genes. Here we analyzed arsenic-Kelch-like ECH-associated protein 1 (Keap1) cysteine thiol interaction in Nrf2 activation. Arsenic-based Nrf2 activators,... |
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Genotoxicity surveillance programme in workers dismantling World War I chemical ammunition.
Int. Arch. Occup. Environ. Health 83(5) , 483-95, (2010) To evaluate the effectiveness of personal protective measures in a dismantling plant for chemical weapons from World War I of the Belgian Defence.Seventeen NIOSH level B-equipped plant workers exposed to arsenic trichloride (AsCl(3)) in combination with phosg... |
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Arsenic compounds as anticancer agents.
Cancer Chemother. Pharmacol. 48 Suppl 1 , S72-6, (2001) In this paper the use of arsenic compounds as anticancer agents in clinical trials and in in vitro investigations is reviewed, including the experience at our institute. Treatment of newly diagnosed and relapsed patients with acute promyelocytic leukemia (APL... |
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Effect of arsenic trioxide on vascular endothelial cell proliferation and expression of vascular endothelial growth factor receptors Flt-1 and KDR in gastric cancer in nude mice.
World J. Gastroenterol. 13(48) , 6498-505, (2007) To investigate the effect of arsenic trioxide (As2O3) on expression of vascular endothelial growth factor receptor-1 (VEGFR-1, Flt-1) and VEGFR-2 (KDR) in human gastric tumor cells and proliferation of vascular endothelial cells.The solid tumor model was form... |