barbital
barbital structure
|
Common Name | barbital | ||
|---|---|---|---|---|
| CAS Number | 57-44-3 | Molecular Weight | 184.193 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 339.7±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H12N2O3 | Melting Point | 188-192ºC | |
| MSDS | Chinese USA | Flash Point | 159.2±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.
J. Physiol. 593(8) , 2097-109, (2015) Sensing of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and behavioural responses. However, the exact physiological pathways linking intestinal fat sensing to food intake and the activation of brain circuits remai... |
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The trenbolone acetate affects the immune system in rainbow trout, Oncorhynchus mykiss.
Aquat. Toxicol. 163 , 109-20, (2015) In aquatic systems, the presence of endocrine-disrupting chemicals (EDC) can disrupt the reproductive function but also the immune system of wildlife. Some studies have investigated the effects of androgens on the fish immune parameters but the mechanisms by ... |
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Recombinant human IgA1 and IgA2 autoantibodies to type VII collagen induce subepidermal blistering ex vivo.
J. Immunol. 193(4) , 1600-8, (2014) Subepidermal autoimmune blistering dermatoses (AIBD) are prototypic autoantibody-mediated diseases. In epidermolysis bullosa acquisita (EBA), an autoimmune disease with severe and chronic skin blistering, autoantibodies are directed against type VII collagen.... |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins
Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the mole... |
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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the... |
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Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Eur. J. Med. Chem. 43 , 478-85, (2008) Values of in vitro gas to lung partition coefficients, K(lung), of VOCs have been collected from the literature. For 44 VOCs, application of the Abraham solvation equation to log K(lung) yielded a correlation with R(2)=0.968 and S.D.=0.25 log units. Combinati... |
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Complementary expression and phosphorylation of Cx46 and Cx50 during development and following gene deletion in mouse and in normal and orchitic mink testes.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 309 , R255-76, (2015) Gap junction-mediated communication helps synchronize interconnected Sertoli cell activities. Besides, coordination of germ cell and Sertoli cell activities depends on gap junction-mediated Sertoli cell-germ cell communication. This report assesses mechanisms... |
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The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.
Nat. Commun. 5 , 5887, (2014) The hallmark of enteropathogenic Escherichia coli (EPEC) infection is the formation of actin-rich pedestal-like structures, which are generated following phosphorylation of the bacterial effector Tir by cellular Src and Abl family tyrosine kinases. This leads... |
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Stabilization of HAC1 influenza vaccine by spray drying: formulation development and process scale-up.
Pharm. Res. 31(11) , 3006-18, (2014) Stable vaccines with long shelf lives and reduced dependency on the cold chain are ideal for stockpiling and rapid deployment during public emergencies, including pandemics. Spray drying is a low-cost process that has potential to produce vaccines stable at a... |