2-(Trifluoromethyl)benzoic acid
2-(Trifluoromethyl)benzoic acid structure
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Common Name | 2-(Trifluoromethyl)benzoic acid | ||
|---|---|---|---|---|
| CAS Number | 433-97-6 | Molecular Weight | 190.119 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 243.7±40.0 °C at 760 mmHg | |
| Molecular Formula | C8H5F3O2 | Melting Point | 110-112ºC | |
| MSDS | Chinese USA | Flash Point | 101.2±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy.
J. Pharm. Biomed. Anal. 8(8-12) , 939-44, (1990)
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Synthesis, characterization and biological activity of some new 1,3,4-oxadiazole bearing 2-flouro-4-methoxy phenyl moiety.
Eur. J. Med. Chem. 45(3) , 1206-10, (2010) In the present study a series of new 1,3,4-oxadiazole derivatives containing 2-fluoro-4-methoxy moiety were synthesized. These newly synthesized compounds were characterized by NMR, mass spectral, IR spectral study and also by C, H, N analyses. All the newly ... |
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Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins.
Org. Biomol. Chem. 2(5) , 725-31, (2004) Identification of compounds from chemical libraries that bind to macromolecules by use of NMR spectroscopy has gained increasing importance during recent years. A simple methodology based on (19)F NMR spectroscopy for the screening of ligands that bind to pro... |
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Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition.
J. Pharm. Biomed. Anal. 13(8) , 971-7, (1995) Many drugs containing carboxylic acid functional groups are metabolised in vivo to ester glucuronides (1-O-acyl-beta-D-glucopyranuronates) and, of these, a number show a propensity to undergo internal isomerisation via a transacylation process, causing the ca... |