H-Gly-Ala-OH

H-Gly-Ala-OH Structure
H-Gly-Ala-OH structure
Common Name H-Gly-Ala-OH
CAS Number 3695-73-6 Molecular Weight 146.145
Density 1.3±0.1 g/cm3 Boiling Point 417.4±30.0 °C at 760 mmHg
Molecular Formula C5H10N2O3 Melting Point ~ 230°C dec.
MSDS Chinese USA Flash Point 206.2±24.6 °C

Charge-based interactions between peptides observed as the dominant force for association in aqueous solution.

Angew. Chem. Int. Ed. Engl. 47(47) , 9059-62, (2008)

Epstein-Barr virus latent genes.

Exp. Mol. Med. 47 , e131, (2015)

Latent Epstein-Barr virus (EBV) infection has a substantial role in causing many human disorders. The persistence of these viral genomes in all malignant cells, yet with the expression of limited latent genes, is consistent with the notion that EBV latent gen...

Dissociative electron attachment to glycyl-glycine, glycyl-alanine and alanyl-alanine.

Phys. Chem. Chem. Phys. 13(10) , 4600-6, (2011)

The processes of negative ions formation of dipeptides glycyl-glycine, glycyl-alanine and alanyl-alanine in the conditions of resonant electron capture have been studied with a help of negative ions mass spectrometry. Using a thermochemical approach, the main...

Direct measurement indicates a slow cis/trans isomerization at the secondary amide peptide bond of glycylglycine.

J. Am. Chem. Soc. 123(26) , 6227-31, (2001)

Spectral differences between the cis and the trans isomer of a secondary amide peptide bond were used to follow the time course of the cis/trans isomerization of Gly-Gly, Gly-Ala, Ala-Gly, and Ala-Ala dipeptides in the UV/vis region at 220 nm. Isomerization r...

Water molecule adsorption on protonated dipeptides.

J. Am. Chem. Soc. 126(4) , 1206-13, (2004)

Equilibrium constants for the adsorption of the first water molecule on six protonated dipeptides (Gly-Gly+H(+), Gly-Ala+H(+), Ala-Gly+H(+), Ala-Ala+H(+), Pro-Gly+H(+), and Gly-Trp+H(+)) have been measured as a function of temperature, and DeltaH(o) and Delta...

[Chiral separation of dipeptides by capillary electrophoresis].

Se Pu 24(2) , 188-91, (2006)

Peptides are increasingly used as pharmaceutical agents. Many small peptides are the essential compounds in biological systems. Direct chiral separation of dipeptide derivatives using 9-(2-carbazole) ethyl chloroformate (CEOC) as the derivatizing agent by cap...

Thermodynamic, kinetic and structural studies on the ternary palladium(II) complexes of thioether ligands.

J. Inorg. Biochem. 79(1-4) , 129-38, (2000)

Potentiometric, calorimetric, NMR and stopped-flow kinetic studies were performed on the palladium(II) complexes of thioether and/or nitrogen donor ligands. The ternary systems always contained a tridentate ligand (dien, terpy and dianions of dipeptides, GlyG...

Peptide aggregation and solvent electrostriction in a simple zwitterionic dipeptide via molecular dynamics simulations.

J. Chem. Phys. 131(1) , 015103, (2009)

We investigate the structure of the glycyl-l-alanine dipeptide in aqueous solution at a 1:20 peptide:water concentration via classical, atomistic molecular dynamics simulations using the CHARMM22 force field, and compare to recent neutron diffraction data [S....

Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.

Biochemistry 44(30) , 9971-9, (2005)

The Streptomyces R61 dd-peptidase, a functional model for penicillin-binding proteins, catalyzes the hydrolysis and aminolysis of d-alanyl-d-alanine-terminating peptides by specific amines. In vivo, this reaction completes bacterial cell wall biosynthesis. Fo...

A multipole-based water potential with implicit polarization for biomolecular simulations.

J. Comput. Chem. 30(6) , 893-9, (2009)

A new water potential, DMIP (distributed multipoles, implicit polarization), is constructed using distributed multipoles to describe the electrostatic interactions, while accounting for polarization implicitly. In this procedure, small clusters are randomly s...