cefsulodin sodium

cefsulodin sodium Structure
cefsulodin sodium structure
Common Name cefsulodin sodium
CAS Number 52152-93-9 Molecular Weight 554.528
Density N/A Boiling Point N/A
Molecular Formula C22H19N4NaO8S2 Melting Point 175ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

A comparative study of the binding characteristics of ceftriaxone, cefoperazone and cefsulodin to human serum albumin.

Biochem. Mol. Biol. Int. 40(4) , 823-31, (1996)

The binding to human serum albumin of three cephalosporins of pharmacological interest: cefoperazone, ceftriaxone and cefsulodin was studied by ultrafiltration and differential scanning calorimetry methods. The identification of the binding sites in albumin w...

Sub-inhibitory cefsulodin sensitization of E. coli to β-lactams is mediated by PBP1b inhibition.

PLoS ONE 7(11) , e48598, (2012)

The combination of antibiotics is one of the strategies to combat drug-resistant bacteria, though only a handful of such combinations are in use, such as the β-lactam combinations. In the present study, the efficacy of a specific sub-inhibitory concentration ...

Growth of pure cultures of Verocytotoxin-producing Escherichia coli in a range of enrichment media.

J. Appl. Microbiol. 105(5) , 1259-65, (2008)

This study compared the growth of different strains of Verocytotoxin-producing Escherichia coli (VTEC) in a range of selective enrichment media.Turbidometric and impedance methods were used to determine the growth of VTEC in pure culture in different enrichme...

Effects of antibiotics on adherence of Pseudomonas aeruginosa and Pseudomonas fluorescens to A549 pneumocyte cells.

Chemotherapy 46(2) , 129-34, (2000)

The aim of this study was to evaluate the effect of antibiotics at subminimal inhibitory concentrations (sub-MIC) on fluorescent pseudomonas adherence to A549 pneumocyte cells. Pseudomonas fluorescens MF0 isolated from contaminated raw milk and Pseudomonas ae...

Effects of antibiotics on adherence of Pseudomonas aeruginosa and Pseudomonas fluorescens to human fibronectin.

Chemotherapy 47(5) , 344-9, (2001)

The effect of subminimal inhibitory concentration (1/2 MIC) of antimicrobial agents on the adherence of fluorescent Pseudomonas to human fibronectin (FN) was investigated by examining two Pseudomonas fluorescens and four Pseudomonas aeruginosa strains. The Es...

Evaluation of Coli-ID and MUG Plus media for recovering Escherichia coli and other coliform bacteria from groundwater samples.

Water Sci. Technol. 43(12) , 213-6, (2001)

Several chromogenic media for detecting coliform bacteria in water are commercially available including Coli ID medium (ID) (bioMérieux) and MUG Plus cefsulodin agar (MP) (Laboratorios Microkit, S.L.). Since little is known about the performance of these medi...

Growth studies of plasmid bearing and plasmid cured Yersinia enterocolitica GER O:3 in the presence of cefsulodin, irgasan and novobiocin at 25 and 37 degrees C.

J. Appl. Microbiol. 100(6) , 1299-306, (2006)

In this study, the growth characteristics of Yersinia enterocolitica biotype 4, GER O:3 plasmid bearing (P+) and plasmid cured (P-) strain types were evaluated in brain heart infusion broth supplemented with cefsulodin, irgasan, and novobiocin alone or in com...

Alterations in high molecular mass penicillin-binding protein 1 associated with beta-lactam resistance in Shigella dysenteriae.

Biochem. Biophys. Res. Commun. 248(3) , 669-72, (1998)

Beta-lactam resistance poses a major problem in the chemotherapy of shigellosis caused by Shigella dysenteriae. Such resistance may arise from alterations in the affinities or amounts of the penicillin-binding proteins (PBPs) for beta-lactams, elaboration of ...

Cefsulodin chocolate blood agar: a selective medium for the recovery of Haemophilus influenzae from the respiratory secretions of patients with cystic fibrosis.

J. Med. Microbiol. 46(10) , 883-5, (1997)

A modified chocolate blood agar medium incorporating cefsulodin, a semi-synthetic cephalosporin, was developed and compared with non-selective chocolate blood agar and selective haemin-bacitracin blood agar for the routine isolation of Haemophilus influenzae ...

Effect of sulbactam on anti-pseudomonal activity of beta-lactam antibiotics in cells producing various levels of the MexAB-OprM efflux pump and beta-lactamase.

Microbiol. Immunol. 44(12) , 997-1001, (2000)

The beta-lactamase inhibitor, sulbactam, was tested for beta-lactamase inhibitory activity in Pseudomonas aeruginosa cells producing various levels of both the MexAB-OprM efflux pump and beta-lactamase. We found that sulbactam lowered the MICs of cefoperazone...