Methyl 8-chloro-8-oxooctanoate

Methyl 8-chloro-8-oxooctanoate Structure
Methyl 8-chloro-8-oxooctanoate structure
Common Name Methyl 8-chloro-8-oxooctanoate
CAS Number 41624-92-4 Molecular Weight 206.66700
Density N/A Boiling Point N/A
Molecular Formula C9H15ClO3 Melting Point N/A
MSDS Chinese USA Flash Point 235.4 °F
Symbol GHS05
GHS05
Signal Word Danger

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors.

ACS Med. Chem. Lett. 2(5) , 358-362, (2011)

N(1)-Hydroxy-N(8)-ferrocenyloctanediamide, JAHA (7), an organometallic analogue of SAHA containing a ferrocenyl group as a phenyl bioisostere, displays nanomolar inhibition of class I HDACs, excellent selectivity over class IIa HDACs, and anticancer action in...

8-cyclopentadienyltricarbonyl 99mtc 8-oxooctanoic acid: a novel radiotracer for evaluation of medium chain fatty acid metabolism in the liver.

Bioconjug. Chem. 15(1) , 121-7, (2004)

8-Cyclopentadienyltricarbonyl 99mTc 8-oxooctanoic acid (99mTc-CpTTOA; 1a) was synthesized for evaluation of medium chain fatty acid metabolism in the liver. 99mTc-CpTTOA was prepared in high radiochemical yield (50-63%) by a double ligand transfer reaction of...

High-performance liquid chromatographic assay with fluorescence detection for the evaluation of inhibitors against fatty acid amide hydrolase.

Anal. Bioanal. Chem 394(6) , 1679-1685, (2009)

A fluorescent assay for the evaluation of inhibitors of fatty acid amide hydrolase (FAAH) is described. Microsomes from rat brain served as enzyme source. N-(2-Hydroxyethyl)-4-pyren-1-ylbutanamide was designed and synthesized as novel fluorogenic substrate. F...

Synthesis and properties of PI polyamide–SAHA conjugate. Ohtsuki et al.

Tetrahedron Lett. 50(52) , 7288-7292, (2009)

Synthesis of 1-Aminocyclopropyl-Pentanoic and-Heptanoic Acid Derivatives. Gensini et al.

Lett. Org. Chem. 5(5) , 328-331, (2008)

A cyclodextrin-capped histone deacetylase inhibitor. Amin et al.

Biochem. Med. 23(11) , 3346-3348, (2013)