2-Methyl-6-nitrobenzoic anhydride
2-Methyl-6-nitrobenzoic anhydride structure
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Common Name | 2-Methyl-6-nitrobenzoic anhydride | ||
|---|---|---|---|---|
| CAS Number | 434935-69-0 | Molecular Weight | 344.276 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 559.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C16H12N2O7 | Melting Point | 177ºC | |
| MSDS | Chinese USA | Flash Point | 246.5±32.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.
Toxicol. Sci. 141(1) , 78-89, (2014) In the present study, a previously established integrated testing strategy (ITS) for in vitro estrogenicity testing was extended with additional in vitro assays in order to broaden its sensitivity to different modes of action resulting in apparent estrogenici... |
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Improved profiling of estrogen metabolites by orbitrap LC/MS.
Steroids 99 , 84-90, (2015) Estrogen metabolites are important biomarkers to evaluate cancer risks and metabolic diseases. Due to their low physiological levels, a sensitive and accurate method is required, especially for the quantitation of unconjugated forms of endogenous steroids and... |
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Limited in vitro efficacy of CYP17A1 inhibition on human castration resistant prostate cancer.
Steroids 92 , 39-44, (2014) Although accumulating evidence indicates high expression of CYP17A1(P45017A1) allows castration resistant prostate cancer (CRPC) to maintain high intratumoral androgen levels, the potential P45017A1 activity has not been characterized yet. The aim of this stu... |
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High testosterone levels in prostate tissue obtained by needle biopsy correlate with poor-prognosis factors in prostate cancer patients.
BMC Cancer 14 , 717, (2014) There is currently no consensus on the correlations between androgen concentrations in prostate tissue and blood and stage and pathological grade of prostate cancer. In this study, we used a newly-developed ultra-sensitive liquid-chromatography tandem mass sp... |
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Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity.
Sci. Rep. 3 , 1268, (2013) Physiologically relevant steroid 5α-reductase (SRD5A) activity that is essential for dihydrotestosterone (DHT) biosynthesis in human castration-resistant prostate cancer (CRPC) has not been fully characterized yet. In this study to ascertain the potential SRD... |
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Low serum dehydroepiandrosterone examined by liquid chromatography-tandem mass spectrometry correlates with poor prognosis in hormone-naïve prostate cancer.
Prostate 76 , 376-82, (2016) There is no consensus on blood adrenal androgen concentrations in men with different stages and pathological grades of prostate cancer. In this study, dehydroepiandrosterone (DHEA) concentrations in blood were examined by ultrasensitive liquid chromatography-... |
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The first total synthesis of (-) and (+)-2-hydroxy-24-oxooctacosanolide using an effective lactonization.
Org. Lett. 8 , 4955, (2006) [structure: see text] An effective method for the total synthesis of 2-hydroxy-24-oxooctacosanolide, a defensive salivary secretion of the African termite Pseudacanthotermes spiniger, has been developed. The key lactonization to form a 29-membered ring lacton... |
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Extraction procedures for the study of phytotoxicity and degradation processes of selected triketones in a water ecosystem.
Environ. Sci. Pollut. Res. Int. 21 , 4751-8, (2014) Simple and effective extraction methods based on matrix solid-phase dispersion (MSPD), dispersive liquid-liquid microextraction (DLLME), and solid-phase extraction (SPE) coupled with high-performance liquid chromatography with diode array detector (HPLC-DAD) ... |