3-methoxybenzyl bromide

3-methoxybenzyl bromide Structure
3-methoxybenzyl bromide structure
Common Name 3-methoxybenzyl bromide
CAS Number 874-98-6 Molecular Weight 201.061
Density 1.4±0.1 g/cm3 Boiling Point 241.1±15.0 °C at 760 mmHg
Molecular Formula C8H9BrO Melting Point N/A
MSDS Chinese USA Flash Point 95.4±21.5 °C
Symbol GHS05
GHS05
Signal Word Danger

Marginally designed new profen analogues have the potential to inhibit cyclooxygenase enzymes.

Arch. Pharm. (Weinheim) 348(1) , 55-61, (2015)

The current structure-activity relationship of profens (i.e., 2-arylpropionic acid derivatives, a class of non-steroidal anti-inflammatory drugs) discusses the importance of α-monomethyl substitution on these compounds, since the activities obtained through t...

Sequential one-pot ruthenium-catalyzed azide-alkyne cycloaddition from primary alkyl halides and sodium azide.

J. Org. Chem. 76(7) , 2355-9, (2011)

An experimentally simple sequential one-pot RuAAC reaction, affording 1,5-disubstituted 1H-1,2,3-triazoles in good to excellent yields starting from an alkyl halide, sodium azide, and an alkyne, is reported. The organic azide is formed in situ by treating the...

Mild conversion of beta-diketones and beta-ketoesters to carboxylic acids.

J. Org. Chem. 71 , 4516-4520, (2006)

A mild protocol for the conversion of beta-ketoesters and beta-diketones to carboxylic acids with use of CAN in CH3CN is described. The method is compatible with a number of functional groups, and can generate carboxylic acids under neutral conditions at room...

Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.

J. Comb. Chem. 11 , 14-33, (2009)

Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective rea...

Highly diastereoselective alkylation of vicinal dianions of chiral succinic acid derivatives: a new general strategy to (R)-ß-arylmethyl-?-butyrolactones. Pohmakotr M, et al.

Tetrahedron Lett. 45(22) , 4315-4318, (2004)

Synthesis of (-)-kainic acid using chiral lithium amides in an asymmetric dearomatizing cyclization. Clayden J, et al.

Tetrahedron 58(23) , 4727-4733, (2002)

Application of sulfur ylide mediated epoxidations in the asymmetric synthesis of ß-hydroxy-d-lactones. Synthesis of a mevinic acid analogue and (+)-prelactone B. Aggarwal VK, et al.

Tetrahedron Asymmetry 60(43) , 9725-9733, (2004)