D-(+)-Trehalose dihydrate
D-(+)-Trehalose dihydrate structure
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Common Name | D-(+)-Trehalose dihydrate | ||
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| CAS Number | 6138-23-4 | Molecular Weight | 378.327 | |
| Density | 1.76 g/cm3 | Boiling Point | 675.4ºC at 760 mmHg | |
| Molecular Formula | C12H26O13 | Melting Point | 97-99 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 362.3ºC | |
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SUMO1 promotes Aβ production via the modulation of autophagy.
Autophagy 11(1) , 100-12, (2015) Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-li... |
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Molecular markers in ambient aerosol in the Mahanadi Riverside Basin of eastern central India during winter.
Environ. Sci. Pollut. Res. Int. 22(2) , 1220-31, (2015) Organic molecular markers are important atmospheric constituents. Their formation and sources are important aspects of the study of urban and rural air quality. We collected PM10 aerosol samples from the Mahanadi Riverside Basin (MRB), a rural part of eastern... |
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Size and molecular flexibility of sugars determine the storage stability of freeze-dried proteins.
Mol. Pharm. 12(3) , 684-94, (2015) Protein-based biopharmaceuticals are generally produced as aqueous solutions and stored refrigerated to obtain sufficient shelf life. Alternatively, proteins may be freeze-dried in the presence of sugars to allow storage stability at ambient conditions for pr... |
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An immunologic test for chronic rhinosinusitis based on free intranasal eosinophilic major basic protein.
Int. Forum Allergy Rhinol. 5(1) , 28-35, (2015) A histologic hallmark of chronic rhinosinusitis (CRS) is an eosinophilic inflammation, present with and without nasal polyposis and independent of atopy. Eosinophils migrate through nasal tissue including the epithelium into the nasal airway mucus, where they... |
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Anionic nanoparticles based on Span 80 as low-cost, simple and efficient non-viral gene-transfection systems.
Int. J. Pharm. 476(1-2) , 23-30, (2015) The existing strategies in the design of non-viral vectors for gene therapy are primarily conceived for cationic systems. However, the safety concerns associated with the use of positively charged systems for nucleic acid delivery and several reports regardin... |
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Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 965 , 65-71, (2014) Deamidation is one of the most common degradation pathways for proteins and frequently occurs at "hot spots" with Asn-Gly, Asn-Ser or Asn-Thr sequences. Occasionally, deamidation may occur at other motifs if the local protein structure can participate or assi... |
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Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness.
MAbs 6(6) , 1439-52, (2014) Corneal transplantation is the primary treatment option to restore vision for patients with corneal endothelial blindness. Although the success rate of treatment is high, limited availability of transplant grade corneas is a major obstacle. Tissue-engineered ... |
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Phytochemical fingerprints of lime honey collected in serbia.
J. AOAC Int. 97(5) , 1259-67, (2015) Composition of phenolic compounds and the sugar content were determined as the basis for characterization of lime honey from Serbia. Particular attention was given to differences in phytochemical profiles of ripe and unripe lime honey and lime tree nectar. Me... |
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Duodenum-triggered delivery of pravastatin sodium via enteric surface-coated nanovesicular spanlastic dispersions: development, characterization and pharmacokinetic assessments.
Int. J. Pharm. 483(1-2) , 77-88, (2015) Pravastatin sodium (PVS) is a hydrophilic HMG-CoA reductase inhibitor that is mainly absorbed from duodenum. PVS has a short elimination half-life (1-3 h), suffers from instability at gastric pH, extensive hepatic first-pass metabolism and low absolute bioava... |
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Uptake and cytotoxicity of docetaxel-loaded hyaluronic acid-grafted oily core nanocapsules in MDA-MB 231 cancer cells.
Pharm. Res. 31(9) , 2439-52, (2014) It is hypothesized that docetaxel (Doc)-loaded hyaluronic acid (HA)-polyethylene glycol/poly(ε-caprolactone)-grafted oily core nanocapsules (NCs) can enhance the drug cytotoxicity and uptake in CD44 expressing breast cancer (BC) cells (MDA-MB 231).NCs were pr... |