Oxirane,2-(phenylmethyl)-
Oxirane,2-(phenylmethyl)- structure
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Common Name | Oxirane,2-(phenylmethyl)- | ||
|---|---|---|---|---|
| CAS Number | 4436-24-2 | Molecular Weight | 134.17500 | |
| Density | 1.094g/cm3 | Boiling Point | 215ºC at 760mmHg | |
| Molecular Formula | C9H10O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 81.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Investigation of the role of the 2',3'-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs.
Toxicology 160 , 47-58, (2001) The genotoxic potential of naturally occurring allylbenzene analogs, including safrole, eugenol, estragole, and others, has been examined in many studies over the past 30 years. It has been established that these compounds are subject to biotransformation in ... |
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Covalent binding to DNA in vitro of 2',3'-oxides derived from allylbenzene analogs.
Drug Metab. Dispos. 24(9) , 1020-7, (1996) Epoxidation at the allylic side chain is a major metabolic pathway for allylbenzene and its naturally occurring analogs safrole, estragole, and eugenol. We demonstrate herein that the epoxide metabolites of allylbenzene, estragole, and safrole can form covale... |
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Detoxication of the 2',3'-epoxide metabolites of allylbenzene and estragole. Conjugation with glutathione.
Drug Metab. Dispos. 22(5) , 731-7, (1994) The enzymatic detoxication in vitro of the 2',3'-epoxide derivatives of allylbenzene and estragole was examined, and the relative rates of enzymatic glutathione conjugation and epoxide hydrolysis were compared with those for styrene 1',2'-oxide. HPLC was used... |