2-Chloro-4-hydroxybenzonitrile

2-Chloro-4-hydroxybenzonitrile Structure
2-Chloro-4-hydroxybenzonitrile structure
Common Name 2-Chloro-4-hydroxybenzonitrile
CAS Number 3336-16-1 Molecular Weight 153.566
Density 1.4±0.1 g/cm3 Boiling Point 323.2±27.0 °C at 760 mmHg
Molecular Formula C7H4ClNO Melting Point 160ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 149.3±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents.

Bioorg. Med. Chem. 19(18) , 5468-79, (2011)

Novel macrocyclic C-aryl glucoside SGLT2 inhibitors were designed and synthesized. Two different synthetic routes of macrocyclization were adopted to prepare novel ansa SGLT2 inhibitors. Among the compounds tested, [1,7]dioxacyclopentadecine macrocycles posse...

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