6-Methylpurine

6-Methylpurine Structure
6-Methylpurine structure
Common Name 6-Methylpurine
CAS Number 2004-03-7 Molecular Weight 134.139
Density 1.4±0.1 g/cm3 Boiling Point 410.9±25.0 °C at 760 mmHg
Molecular Formula C6H6N4 Melting Point 237-238ºC(lit.)
MSDS Chinese USA Flash Point 212.7±16.1 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Accumulation of 19 environmental phenolic and xenobiotic heterocyclic aromatic compounds in human adipose tissue.

Environ. Int. 78 , 45-50, (2015)

The extensive use of environmental phenols (e.g., bisphenol A) and heterocyclic aromatic compounds (e.g., benzothiazole) in consumer products as well as widespread exposure of humans to these compounds have been well documented. Biomonitoring studies have use...

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune diseases, infertility, cancer. Fifteen widely used industri...

Spatial distribution, temporal variation and risks of parabens and their chlorinated derivatives in urban surface water in Beijing, China.

Sci. Total Environ. 539 , 262-70, (2015)

The occurrence and distribution of 13 target compounds, including eight parabens, four chlorinated parabens and p-hydroxybenzoic acid (PHBA), were detected in surface water samples at 35 sampling sites in the Beijing River system, China. The surface water sam...

Occurrence and human exposure of parabens and their chlorinated derivatives in swimming pools.

Environ. Sci. Pollut. Res. Int. 22 , 17987-97, (2015)

As an emerging group of endocrine-disrupting chemicals, parabens have attracted growing attention due to their potential effects on human health. In the present study, the occurrence and distribution of eight parabens, four chlorinated parabens, and their com...

Improved sensitivity gas chromatography-mass spectrometry determination of parabens in waters using ionic liquids.

Talanta 146 , 568-74, (2015)

A new procedure for the introduction of ionic liquid samples in gas chromatography (GC) is proposed. This procedure, based on microvial insert thermal desorption, allows the direct analysis of the compounds preconcentrated by ionic liquid based liquid-liquid ...

Convenient syntheses of 6-methylpurine and related nucleosides.

Nucleosides Nucleotides Nucleic Acids 19(7) , 1123-34, (2000)

Efficient methods for the synthesis of 6-methylpurine (3), 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-methylpurine (8), and 6-methyl-9-beta-D-ribofuranosylpurine (5) are described. Methodology involving the (Ph3P)4Pd catalyzed cross-coupling reaction of CH3Z...

Interaction of plant growth regulators and reactive oxygen species to regulate petal senescence in wallflowers (Erysimum linifolium).

BMC Plant Biol. 16 , 77, (2016)

In many species floral senescence is coordinated by ethylene. Endogenous levels rise, and exogenous application accelerates senescence. Furthermore, floral senescence is often associated with increased reactive oxygen species, and is delayed by exogenously ap...

Occurrence of phthalate diesters (phthalates), p-hydroxybenzoic acid esters (parabens), bisphenol A diglycidyl ether (BADGE) and their derivatives in indoor dust from Vietnam: Implications for exposure.

Chemosphere 144 , 1553-9, (2015)

Phthalate diesters (phthalates), esters of p-hydroxybenzoic acid (parabens), and bisphenol A diglycidyl ether (BADGE) are used in personal care products, food packages, household products, or pharmaceuticals. These compounds possess endocrine-disrupting poten...

Synthetic Phenolic Antioxidants and Their Metabolites in Indoor Dust from Homes and Microenvironments.

Environ. Sci. Technol. 50 , 428-34, (2016)

Synthetic phenolic antioxidants (SPAs), including 2,6-di-tert-butyl-4-hydroxytoluene (BHT), are extensively used in food, cosmetic and plastic industries. Nevertheless, limited information is available on human exposures, other than the dietary sources, to SP...

Ultrasound-assisted hydrolysis of conjugated parabens in human urine and their determination by UPLC-MS/MS and UPLC-HRMS.

Anal. Bioanal. Chem 408 , 1573-83, (2016)

Parabens are preservatives widely used in personal care products, pharmaceutical formulations as well as in food, and they are considered endocrine disruptors. For application in biomonitoring studies we developed a method for the determination of eight parab...