guanosine 5'-diphosphate sodium salt

guanosine 5'-diphosphate sodium salt Structure
guanosine 5'-diphosphate sodium salt structure
Common Name guanosine 5'-diphosphate sodium salt
CAS Number 43139-22-6 Molecular Weight 465.18200
Density N/A Boiling Point N/A
Molecular Formula C10H14N5NaO11P2 Melting Point N/A
MSDS USA Flash Point N/A

A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.

J. Chromatogr. A. 1360 , 240-7, (2014)

Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due to the presence of the glucose structure and charged quater...

ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence.

Biochim. Biophys. Acta 1837(12) , 2017-30, (2014)

Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The issue is of principal significance, as it can be seen as a proof- or disproof-of-principle concerning the ability of any protein to diminish ROS production t...

Differential kinetics at PK/PEPCK branch point in the cestode, Raillietina echinobothrida.

Exp. Parasitol. 153 , 151-9, (2015)

Pyruvate kinase (PK; EC 2.7.1.40) and phosphoenolpyruvate carboxykinase (PEPCK; EC 4.1.1.32) are essential regulatory enzymes of glucose oxidation in helminths, the PK/PEPCK branch point being the first divergent step between carbohydrate catabolism of the pa...

Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation.

EMBO J. 30 , 3913-3927, (2011)

The activation of the Rac1 GTPase during cell signalling entails its translocation from the cytosol to membranes, release from sequestering Rho GDP dissociation inhibitors (RhoGDI), and GDP/GTP exchange. In addition to those steps, we show here that optimal R...

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 189 , 165-176, (2011)

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits. Recently, facilitated GDP/GTP exchange by non-GPCR GEFs, ...

Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.

J. Biol. Chem. 286 , 35163-35175, (2011)

PDZRhoGEF (PRG) belongs to a small family of RhoA-specific nucleotide exchange factors that mediates signaling through select G-protein-coupled receptors via Gα(12/13) and activates RhoA by catalyzing the exchange of GDP to GTP. PRG is a multidomain protein c...

Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation.

J. Biol. Chem. 286(42) , 36898-906, (2011)

ADP-ribosylation factors (ARFs) and their activating guanine nucleotide exchange factors (GEFs) play key roles in membrane traffic and signaling. All ARF GEFs share a ∼200-residue Sec7 domain (Sec7d) that alone catalyzes the GDP to GTP exchange that activates...

The eubacterial protein synthesis inhibitor pulvomycin interacts with archaeal elongation factor 1α from Sulfolobus solfataricus.

Biochimie 94(2) , 503-9, (2011)

The effect of pulvomycin on the biochemical and fluorescence spectroscopic properties of the archaeal elongation factor 1α from Sulfolobus solfataricus (SsEF-1α), the functional analog of eubacterial EF-Tu, was investigated. The antibiotic was able to reduce ...

Enhanced A3 adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates.

J. Nanobiotechnology 6 , 12, (2008)

An approach to use multivalent dendrimer carriers for delivery of nucleoside signaling molecules to their cell surface G protein-coupled receptors (GPCRs) was recently introduced.A known adenosine receptor (AR) agonist was conjugated to polyamidoamine (PAMAM)...