43139-22-6

43139-22-6 structure

Name: guanosine 5'-diphosphate sodium salt
Chemical Name: guanosine 5'-diphosphate sodium salt
CAS Number: 43139-22-6
Molecular Formula: C₁₀H₁₄N₅NaO₁₁P₂
Molecular Weight: 465.18200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2018-06-24 17:31:08
Modify Date: 2024-01-02 21:58:51
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].

Name	guanosine 5'-diphosphate sodium salt
Synonyms	guanosine 5'-diphosphate sodium salt,Type I GUANOSINE-5'-DIPHOSPHATE MONOSODIUM SALT guanosine 5'-diphosphate sodium type I 5'-GDP 3NA GUANOSINE-5'-DIPHOSPHATE SODIUM SALT ULTRA PURE GRADE Guanosine-5''-diphosphoric acid monosodium salt

Description	Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	Human Endogenous Metabolite
References	[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. [2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.

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