D-Pinitol
D-Pinitol structure
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Common Name | D-Pinitol | ||
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| CAS Number | 10284-63-6 | Molecular Weight | 194.182 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 317.2±42.0 °C at 760 mmHg | |
| Molecular Formula | C7H14O6 | Melting Point | 178-185ºC | |
| MSDS | Chinese USA | Flash Point | 145.6±27.9 °C | |
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Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats.
Free Radic. Res. 44(6) , 668-78, (2010) The present study was aimed to investigate the effect of D-pinitol on hyperglycaemia mediated oxidative stress by analysing the hepatic antioxidant competence, pro-inflammatory cytokines and ultrastructural changes in liver tissues of streptozotocin-induced d... |
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The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals.
Int. Immunopharmacol. 11(2) , 286-91, (2011) Argyrolobium roseum (Papilionaceae) is a sexually reproducing, rare, annual herb that grows in tropical and sub-temperate tracts of the north-western Himalayan region of the Indian subcontinent. The present investigation was carried out to study the immunomod... |
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Determination of D-pinitol in carob syrup.
Int. J. Food Sci. Nutr. 62(6) , 572-6, (2011) Carob syrup is a traditional product native to the Mediterranean region, containing a high concentration of sugar, phenolic compounds and minerals. d-pinitol is a bioactive component extracted from legumes and has some beneficial effects on human metabolism. ... |
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Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats.
Eur. J. Pharmacol. 622(1-3) , 65-70, (2009) The present study was aimed to investigate the possible pancreatic tissue protective nature of D-Pinitol, a cyclitol present in soybean, against free radical-mediated oxidative stress in streptozotocin-induced diabetic rats by assaying the activity of pancrea... |
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A single acute dose of pinitol from a naturally-occurring food ingredient decreases hyperglycaemia and circulating insulin levels in healthy subjects.
Food Chem. 141(2) , 1267-72, (2013) A limited amount of research suggests that oral ingestion of pinitol (3-O-methyl-d-chiro-inositol) positively influences glucose tolerance in humans. This study assessed the effects of different doses of pinitol supplementation on glucose tolerance, insulin s... |
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Effects of pinitol on glycemic control, insulin resistance and adipocytokine levels in patients with type 2 diabetes mellitus.
Ann. Nutr. Metab. 60(1) , 1-5, (2012) Pinitol is thought to mediate insulin action and improve insulin resistance. We evaluated the effects of pinitol on glycemic control, insulin resistance and adipocytokine levels in type 2 diabetic patients.A total of 66 patients with type 2 diabetes who had b... |
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D-chiro-inositol affects accumulation of raffinose family oligosaccharides in developing embryos of Pisum sativum.
J. Plant Physiol. 168(4) , 352-8, (2011) Developing garden pea embryos are able to take up exogenously applied cyclitols: myo-inositol, which naturally occurs in pea, and two cyclitols absent in pea plants: d-chiro-inositol and d-pinitol. The competition in the uptake of cyclitols by pea embryo, ins... |
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D-pinitol inhibits RANKL-induced osteoclastogenesis.
Int. Immunopharmacol. 12(3) , 494-500, (2012) Numerous studies have indicated that inflammatory cytokines play a major role in osteoclastogenesis, leading to the bone resorption that is frequently associated with osteoporosis. D-pinitol, a 3-methoxy analogue of D-chiroinositol, was identified as an activ... |
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The effects of creatine monohydrate supplementation with and without D-pinitol on resistance training adaptations.
J. Strength Cond. Res. 23(9) , 2673-82, (2009) Coingestion of D-pinitol with creatine (CR) has been reported to enhance creatine uptake. The purpose of this study was to evaluate whether adding D-pinitol to CR affects training adaptations, body composition, whole-body creatine retention, and/or blood safe... |
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Semi-synthetic analogs of pinitol as potential inhibitors of TNF-alpha cytokine expression in human neutrophils.
Bioorg. Med. Chem. Lett. 19 , 1939-43, (2009) Semi-synthetic analogs of pinitol were subjected to screening by determining TNF-alpha expression in human neutrophils using flowcytometry. Among the tested compounds, three derivatives displayed more than 50% inhibition of TNF-alpha cytokine secretion in LPS... |