2-Phenylbenzothiazole
2-Phenylbenzothiazole structure
|
Common Name | 2-Phenylbenzothiazole | ||
|---|---|---|---|---|
| CAS Number | 883-93-2 | Molecular Weight | 211.282 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 356.9±25.0 °C at 760 mmHg | |
| Molecular Formula | C13H9NS | Melting Point | 111-113 °C(lit.) | |
| MSDS | USA | Flash Point | 174.4±12.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Novel amidino substituted 2-phenylbenzothiazoles: synthesis, antitumor evaluation in vitro and acute toxicity testing in vivo.
Bioorg. Med. Chem. 18(3) , 1038-44, (2010) The efficient synthesis of new bis-substituted nitro-amidino, amino-amidino (10a, 10b-13a, 13b) and previously prepared diamidino 2-phenyl-benzothiazoles (9a, 9b) is described. The compounds 11a and 11b were prepared by recently developed methodology of the k... |
|
|
Design, synthesis and structure-activity relationship of rhenium 2-arylbenzothiazoles as β-amyloid plaque binding agents.
Bioorg. Med. Chem. Lett. 23(6) , 1720-6, (2013) To continue our efforts toward the development of (99m)Tc PiB analogs, we have synthesized 24 neutral and lipophilic Re (as a surrogate of (99m)Tc) 2-arylbenzothiazoles, and explored their structure-activity relationship for binding to Aβ1-40 fibrils. These R... |
|
|
Iridium(III) complexes with enhanced film amorphism as guests for efficient orange solution-processed single-layer PhOLEDs with low efficiency roll-off.
Dalton Trans. 42(29) , 10559-71, (2013) By introducing a phenyl substituent into the meta-site of the phenyl segment of the 2-phenylbenzothiazole ligand, two novel orange iridium(III) complexes, namely, (3Phbt)2Ir(acac) and (3OMePhbt)2Ir(acac), have been synthesized. Compared with their parent comp... |
|
|
Fine tuning of emission color of iridium(III) complexes from yellow to red via substituent effect on 2-phenylbenzothiazole ligands: synthesis, photophysical, electrochemical and DFT study.
Dalton Trans. 40(27) , 7153-64, (2011) Four novel iridium(III) complexes bearing biphenyl (7a-7c) or fluorenyl (7d) modified benzothiazole cyclometallate ligands are synthesized. In comparison with the yellow parent complex, bis(2-phenylbenzothiozolato-N,C(2')) iridium(III) (acetylacetonate) [(pbt... |
|
|
Synthesis and beta-amyloid binding properties of rhenium 2-phenylbenzothiazoles.
Bioorg. Med. Chem. Lett. 19(8) , 2258-62, (2009) As a first step toward the development of (99m)Tc PiB analogs, we have synthesized six neutral Re 2-phenylbenzothiazoles via pendant or integrated approach. These Re compounds bind to Abeta(1-40) fibrils with fairly good affinities (K(i)=10.0-88.6nM) and have... |
|
|
Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents.
Bioorg. Med. Chem. Lett. 22(17) , 5424-7, (2012) A new series of isoxazoles and triazoles linked 2-phenyl benzothiazole were synthesized and evaluated for their anticancer activity. These compounds have been tested for their cytotoxicity three cancer cell lines. Among the compounds tested, compound 5d showe... |
|
|
Oxorhenium(V) and oxotechnetium(V) [NN][S]3 complexes of 2-phenylbenzothiazole derivatives.
Inorg. Chem. 45(2) , 902-9, (2006) The reaction of 2-(2'-pyridyl)benzothiazole, [NN], with the ReO(V)(3+) and TcO(V)(3+) cores in the presence of thiophenols, [S] (RC(6)H(4)SH, R = H, 4-CH(3), 4-OCH(3)), as coligands led to the isolation of hexacoordinated complexes of the MO[NN][S](3) type (M... |
|
|
Modulation of firefly luciferase stability and impact on studies of gene regulation.
Gene 103(2) , 171-7, (1991) Two of the reporter enzymes most commonly used in studies of eukaryotic gene expression are chloramphenicol acetyl-transferase (CAT) and firefly luciferase (Luc). CAT has a half-life of about 50 h in mammalian cells, making it useful for transient transfectio... |
|
|
Study on changes in optical properties of phenylbenzothiazole derivatives on metal ion binding.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 77(1) , 126-9, (2010) The UV-visible and fluorescence properties of hydroxy substituted benzothiazole derivatives change on interactions with zinc(II), cadmium(II) and mercury(II) ions. The binding of 2-(2'-hydroxyphenyl)benzothiazole is specific to zinc(II) over cadmium(II) and m... |
|
|
Synthesis and photophysical properties of yellow-emitting iridium complexes. Effect of the temperature on the character of triplet emission.
J. Fluoresc. 22(6) , 1501-7, (2012) The parent study includes synthesis end photophysical characterization of four new phosphorescent cyclometalated iridium (III) complexes. The cyclometaled ligands used here are 2-(4-chlorophenyl)benzo[d]thiazole, 2(4isopropylphenyl)benzo[d] thiazole, 2-(4-met... |