1,6-Bis(p-carboxyphenoxy)hexane
1,6-Bis(p-carboxyphenoxy)hexane structure
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Common Name | 1,6-Bis(p-carboxyphenoxy)hexane | ||
|---|---|---|---|---|
| CAS Number | 74774-53-1 | Molecular Weight | 358.385 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 580.1±35.0 °C at 760 mmHg | |
| Molecular Formula | C20H22O6 | Melting Point | 278-290 ℃ | |
| MSDS | Chinese USA | Flash Point | 205.7±19.4 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.
Int. J. Nanomedicine 10 , 229-43, (2015) H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhyd... |
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Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.
PLoS Negl. Trop. Dis. 9 , e0004173, (2015) Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. ... |
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Upregulation of FLJ10540, a PI3K-association protein, in rostral ventrolateral medulla impairs brain stem cardiovascular regulation during mevinphos intoxication.
Biochem. Pharmacol. 93(1) , 34-41, (2015) FLJ10540, originally identified as a microtubule-associated protein, induces cell proliferation and migration during tumorigenesis via the formation of FLJ10540-PI3K complex and enhancement of PI3K kinase activity. Interestingly, activation of PI3K/Akt cascad... |
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Anti-inflammatory activity of Chios mastic gum is associated with inhibition of TNF-alpha induced oxidative stress.
Nutr. J. 10 , 64, (2011) Gum of Chios mastic (Pistacia lentiscus var. chia) is a natural antimicrobial agent that has found extensive use in pharmaceutical products and as a nutritional supplement. The molecular mechanisms of its anti-inflammatory activity, however, are not clear. In... |
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Design of an injectable system based on bioerodible polyanhydride microspheres for sustained drug delivery.
Biomaterials 23 , 4405, (2002) The fabrication, morphological characterization, and drug release kinetics from microspheres of three bioerodible polyanhydrides, poly[1,6-bis(p-carboxyphenoxy)hexane] (poly(CPH)), poly(sebacic anhydride) (poly(SA)), and the copolymer poly(CPH-co-SA) 50:50 (C... |
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Network modeling of BVD transmission.
Vet. Res. 43 , 11, (2012) Endemic diseases of cattle, such as bovine viral diarrhea, have significant impact on production efficiency of food of animal origin with consequences for animal welfare and climate change reduction targets. Many modeling studies focus on the local scale, exa... |
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A novel electron paramagnetic resonance-based assay for prostaglandin H synthase-1 activity.
J. Inflamm. (Lond.) 3 , 12, (2006) Prostaglandin H2 synthase (PGHS) is the enzyme that catalyses the two-stage conversion of arachidonic acid to prostaglandin H2 (PGH2) prior to formation of prostanoids that are important in inflammation. PGHS isozymes (-1 and -2) are the target for nonsteroid... |
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Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.
Nat. Commun. 3 , 649, (2012) Lung ischaemia-reperfusion-induced oedema (LIRE) is a life-threatening condition that causes pulmonary oedema induced by endothelial dysfunction. Here we show that lungs from mice lacking nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox2(y/-))... |
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Spatial distribution of the active surveillance of sheep scrapie in Great Britain: an exploratory analysis.
BMC Vet. Res. 5 , 23, (2009) This paper explores the spatial distribution of sampling within the active surveillance of sheep scrapie in Great Britain. We investigated the geographic distribution of the birth holdings of sheep sampled for scrapie during 2002 - 2005, including samples tak... |
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Classical sheep scrapie in Great Britain: spatial analysis and identification of environmental and farm-related risk factors.
BMC Vet. Res. 5 , 33, (2009) Previous studies suggest that the spatial distribution of classical sheep scrapie in Great Britain is uneven and that certain flock characteristics may be associated with occurrence of the disease. However, the existence of areas of high and low disease-risk ... |