Tropinone
Tropinone structure
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Common Name | Tropinone | ||
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| CAS Number | 532-24-1 | Molecular Weight | 139.195 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 217.1±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H13NO | Melting Point | 40-44 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 90.0±0.0 °C | |
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Toxicity of field bindweed (Convolvulus arvensis) to mice.
Vet. Hum. Toxicol. 37(5) , 452-4, (1995) The effects of feeding high and low doses of field bindweed (Convolvulus arvensis) to mice were investigated. Bindweed contains several alkaloids, including pseudotropine, and lesser amounts of tropine, tropinone, and meso-cuscohygrine. Mice fed bindweed excl... |
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Synthesis and applications of masked oxo-sulfinamides in asymmetric synthesis.
Org. Biomol. Chem. 10(26) , 5021-31, (2012) This short perspective reports on the synthesis and applications of a class of chiral amino carbonyl compounds, masked oxo-sulfinamides where the amine is protected with an N-sulfinyl moiety and the carbonyl group is protected as the ketal or 1,3-dithiane. Th... |
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Biosynthesis of calystegines: 15N NMR and kinetics of formation in root cultures of Calystegia sepium.
Phytochemistry 62(3) , 325-32, (2003) Calystegines are nortropane alkaloids bearing between three and five hydroxyl groups in various positions. [15N]Tropinone was administered to root cultures of Calystegia sepium and the incorporation into calystegines was followed. Increase of label in calyste... |
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Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.
Neurosci. Lett. 378(3) , 140-4, (2005) The alpha7 nicotinic acetylcholine receptor (nAChR)-selective partial agonist tropisetron is a conjugate of an indole and a tropane group. We tested compounds structurally related to either the indole or tropane domains of tropisetron on oocytes expressing hu... |
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Total synthesis of (±)-parvineostemonine.
Chem. Asian J. 7(10) , 2199-202, (2012)
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An approach for synthesis of tropinone analogue N-substituted with triazine ring.
Acta Pol. Pharm. 65(6) , 749-51, (2008)
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Organic chemistry: synthesis undressed.
Nature 446(7134) , 383-5, (2007)
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Images in cardiovascular medicine. A rare form of midventricular Tako-Tsubo after emotional stress followed up with magnetic resonance imaging.
Circulation 114(7) , e248, (2006)
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Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc. Natl. Acad. Sci. U. S. A. 95(9) , 4876-81, (1998) A pair of tropinone reductases (TRs) share 64% of the same amino acid residues and belong to the short-chain dehydrogenase/reductase family. In the synthesis of tropane alkaloids in several medicinal plants, the TRs reduce a carbonyl group of an alkaloid inte... |
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Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists.
J. Med. Chem. 41(17) , 3220-31, (1998) A number of O-alkynyloximes of tropinone and N-methyl-4-piperidinone have been synthesized and evaluated for muscarinic activity. The affinities of these oximes were tested in homogenates of cerebral cortex, heart, and submandibulary glands from rats using [3... |