Citral
Citral structure
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Common Name | Citral | ||
|---|---|---|---|---|
| CAS Number | 5392-40-5 | Molecular Weight | 152.233 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 229.0±9.0 °C at 760 mmHg | |
| Molecular Formula | C10H16O | Melting Point | < -10ºC | |
| MSDS | Chinese USA | Flash Point | 101.7±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Two types of alcohol dehydrogenase from Perilla can form citral and perillaldehyde.
Phytochemistry 104 , 12-20, (2014) Studies on the biosynthesis of oil compounds in Perilla will help in understanding regulatory systems of secondary metabolites and in elucidating reaction mechanisms for natural product synthesis. In this study, two types of alcohol dehydrogenases, an aldo-ke... |
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Heterogeneous nucleation and shape transformation of multicomponent metallic nanostructures.
Nat. Mater. 14(2) , 215-23, (2015) To be able to control the functions of engineered multicomponent nanomaterials, a detailed understanding of heterogeneous nucleation at the nanoscale is essential. Here, by using in situ synchrotron X-ray scattering, we show that in the heterogeneous nucleati... |
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Effect of citral on the cytotoxicity of doxorubicin in human B-lymphoma cells.
Pharm. Biol. 53(2) , 262-8, (2015) Doxorubicin is a chemotherapy agent used in non-Hodgkin's lymphoma but side effects limit its use. Citral is a mixture of neral and geranial found in essential oils of lemon grass.We evaluated the activity of citral, doxorubicin, and combination on cytotoxici... |
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Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site.
Mol. Pharmacol. 87(1) , 87-95, (2015) In common with other members of the Cys-loop family of pentameric ligand-gated ion channels, 5-hydroxytryptamine type 3 receptors (5-HT3Rs) are activated by the binding of a neurotransmitter to an extracellular orthosteric site, located at the interface of tw... |
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Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours.
Br. J. Haematol. 168(2) , 246-57, (2015) The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway. We detected aberrant expression of ALDH1A genes, particularly ALDH1A2, in a majority (72%) of primary paedia... |
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A fluorescence high throughput screening method for the detection of reactive electrophiles as potential skin sensitizers.
Toxicol. Appl. Pharmacol. 289 , 177-84, (2015) Skin sensitization is an important toxicological end-point in the risk assessment of chemical allergens. Because of the complexity of the biological mechanisms associated with skin sensitization, integrated approaches combining different chemical, biological ... |
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Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport.
Nat. Commun. 6 , 7476, (2015) All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR). We showed that transcription factor Zic1, expressed at the anterior neural plate, is necessary and sufficient to promote placode f... |
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Apoptosis-inducing effects of Melissa officinalis L. essential oil in glioblastoma multiforme cells.
Cancer Invest. 32(6) , 226-35, (2014) Current therapies for glioblastoma multiforme (GBM) are not effective. This study investigated the activity of the M. officinalis essential oil (EO) and its major component (citral) in GBM cell lines. Both EO and citral decreased the viability and induced apo... |
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Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea.
Nat. Commun. 5 , 3840, (2014) Precise frequency discrimination is a hallmark of auditory function in birds and mammals and is required for distinguishing similar sounding words, like 'bat,' 'cat' and 'hat.' In the cochlea, tuning and spectral separation result from longitudinal difference... |
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Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors
Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009) The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and ketone inhibitors of fatty acid amide hydrolase (FAAH) have bee... |