1,1,3-Trichloroacetone

1,1,3-Trichloroacetone Structure
1,1,3-Trichloroacetone structure
Common Name 1,1,3-Trichloroacetone
CAS Number 921-03-9 Molecular Weight 161.414
Density 1.5±0.1 g/cm3 Boiling Point 170.7±25.0 °C at 760 mmHg
Molecular Formula C3H3Cl3O Melting Point 9-11 °C(lit.)
MSDS Chinese USA Flash Point 79.4±0.0 °C
Symbol GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
Signal Word Danger

Determination of 14 haloketones in treated water using solid-phase microextraction and gas chromatography-mass spectrometry.

J. Chromatogr. A. 1407 , 208-15, (2015)

Haloketones (HKs) are unregulated volatile disinfection by-products that show some potential risk even at low concentrations. While EPA Method 551.1 involves conventional liquid-liquid extraction and a complex series of steps, the simple scientific principles...

Carcinogenic activity associated with halogenated acetones and acroleins in the mouse skin assay.

Cancer Lett. 48(3) , 197-203, (1989)

Several chlorinated acetones have been identified in drinking water and these, as well as a number of chlorinated acroleins, are produced by chlorination of humic acid solutions. Many of these chlorinated compounds and the brominated acrolein analog were posi...

Activity of 1,1,1- and 1,1,3-trichloroacetones in a chromosomal aberration assay in CHO cells and the micronucleus and spermhead abnormality assays in mice.

Mutat. Res. 206(4) , 431-8, (1988)

1,1,1- and 1,1,3-trichloroacetones (TCA) result from the disinfection of municipal water supplies with chlorine, and are direct-acting mutagens in the Ames/Salmonella assay. The objective of this study was to further investigate the genotoxicity of these comp...

Base-Induced Solvolyses of [3.2. 1] Bicyclic a, a'-Dichloro Ketones- 1, 3-Transposition and Ring-Contraction. Föhlisch B, et al.

European J. Org. Chem. 2001(22) , 4357-4365, (2001)