7-Hydroxyquetiapine

7-Hydroxyquetiapine Structure
7-Hydroxyquetiapine structure
Common Name 7-Hydroxyquetiapine
CAS Number 139079-39-3 Molecular Weight 399.50700
Density 1.33 g/cm3 Boiling Point 612.4ºC at 760 mmHg
Molecular Formula C21H25N3O3S Melting Point 56-60ºC
MSDS N/A Flash Point 324.2ºC
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

Determination of an antipsychotic agent (ICI 204,636) and its 7-hydroxy metabolite in human plasma by high-performance liquid chromatography and gas chromatography-mass spectrometry.

J. Chromatogr. A. 573(1) , 49-57, (1992)

ICI 204,636 (I) is an orally active antipsychotic agent under development for the treatment of schizophrenia in humans. It is partially converted in animals to an active 7-hydroxy metabolite (II). Methods were developed for the simultaneous determination of b...