Bumetanide
Bumetanide structure
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Common Name | Bumetanide | ||
|---|---|---|---|---|
| CAS Number | 28395-03-1 | Molecular Weight | 364.416 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 571.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C17H20N2O5S | Melting Point | 230-2310C | |
| MSDS | Chinese USA | Flash Point | 299.3±32.9 °C | |
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Ion channel expression in the developing enteric nervous system.
PLoS ONE 10(3) , e0123436, (2015) The enteric nervous system arises from neural crest-derived cells (ENCCs) that migrate caudally along the embryonic gut. The expression of ion channels by ENCCs in embryonic mice was investigated using a PCR-based array, RT-PCR and immunohistochemistry. Many ... |
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Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns.
Cell Death Dis. 5 , e1494, (2014) Apoptosis, which is anti-inflammatory, and necrosis, which is pro-inflammatory, represent the extremes of the cell death spectrum. Cell death is complex and both apoptosis and necrosis can be observed in the same cells or tissues. Here, we introduce a novel c... |
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Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC-MS/MS.
Forensic Sci. Int. 243 , 35-43, (2014) The aim of this study was to develop an LC-MS/MS based screening technique that covers a broad range of acidic and neutral drugs and poisons by combining a small sample volume and efficient extraction technique with simple automated data processing. After pro... |
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Improving AM ester calcium dye loading efficiency.
J. Neurosci. Methods 240 , 48-60, (2014) Calcium imaging has unraveled the calcium-dependent mechanisms underlying neuronal function. Acetoxymethyl ester (AM) dyes are widely employed for calcium imaging. Pluronic F127 (PF127) as a surfactant and dimethyl sulfoxide (DMSO) as a solvent are used to di... |
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Excretion of NaCl and KCl loads in mosquitoes. 2. Effects of the small molecule Kir channel modulator VU573 and its inactive analog VU342.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(7) , R850-61, (2014) The effect of two small molecules VU342 and VU573 on renal functions in the yellow fever mosquito Aedes aegypti was investigated in vitro and in vivo. In isolated Malpighian tubules, VU342 (10 μM) had no effect on the transepithelial secretion of Na(+), K(+),... |
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. I: Investigation of mobile phase and MS conditions.
Anal. Chim. Acta 853 , 637-46, (2014) The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic doping agents was analyzed, in both ESI+ and ESI- modes. Th... |
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Effects of 5-hydroxymethyl-2-furfural on the volume and membrane permeability of red blood cells from patients with sickle cell disease.
J. Physiol. 592(Pt 18) , 4039-49, (2014) The heterocyclic aldehyde 5-hydroxymethyl-2-furfural (5HMF) interacts allosterically with the abnormal form of haemoglobin (Hb), HbS, in red blood cells (RBCs) from patients with sickle cell disease (SCD), thereby increasing oxygen affinity and decreasing HbS... |
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Clinical outcomes in low risk coronary artery disease patients treated with different limus-based drug-eluting stents--a nationwide retrospective cohort study using insurance claims database.
PLoS ONE 10(4) , e0122860, (2015) The clinical outcomes of different limus-based drug-eluting stents (DES) in a real-world setting have not been well defined. The aim of this study was to investigate the clinical outcomes of three different limus-based DES, namely sirolimus-eluting stent (SES... |
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Glycine transporter-1 controls nonsynaptic inhibitory actions of glycine receptors in the neonatal rat hippocampus.
J. Neurosci. 34(30) , 10003-9, (2014) Although functional glycinergic synapses have not been identified in the hippocampus, neurons in this area express Cl(-) permeable extrasynaptic glycine receptors (GlyRs). In experiments on CA3 pyramidal neurons on postnatal day 0-6 rat hippocampal slices, we... |
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Ultra high performance supercritical fluid chromatography coupled with tandem mass spectrometry for screening of doping agents. II: Analysis of biological samples.
Anal. Chim. Acta 853 , 647-59, (2014) The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, nam... |