Bethanechol chloride
Bethanechol chloride structure
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Common Name | Bethanechol chloride | ||
|---|---|---|---|---|
| CAS Number | 590-63-6 | Molecular Weight | 196.68 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H17ClN2O2 | Melting Point | 187-190ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Characterization of the motor inhibitory role of colonic mucosa under chemical stimulation in mice.
Am. J. Physiol. Gastrointest. Liver Physiol. 306(7) , G614-21, (2014) The main roles of the colonic mucosa are the absorption of water and electrolytes and the barrier function that preserves the integrity of the colonic wall. The mediators and mechanisms to accomplish these functions are under continuous investigation, but lit... |
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Exogenous activation of muscarinic receptors decreases subsequent non-muscarinic bladder contractions in vivo in the female rat.
Life Sci. 92(12) , 733-9, (2013) To determine if the muscarinic agonist, bethanechol, inhibits the non-cholinergic, atropine-resistant (i.e. putatively purinergic) component of naturally occurring (i.e. reflexogenic) bladder contractions in vivo in the rat, as previously described in vitro. ... |
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Characterization of a refinement of the "pylorus ligation" model of rat gastric ulceration resulting in "no pain" and a more specific pharmacological response.
J. Pharmacol. Toxicol. Methods 67(2) , 121-8, (2013) The pharmacological assessment of the factors for gastric protection of a test substance should involve experimental models that can determine the involvement of cytoprotective factors, as well as their influence on the secretion of hydrochloric acid. The ori... |
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The effect of boric acid on acethylcholine, bethanechol and potasssium-evoked responses on ileum of rat.
Auton. Autacoid Pharmacol. 31(3-4) , 50-6, (2011) 1 The aim of this study was to clarify the effect of boric acid on contractions of rat isolated ileum. 2 Contractile responses expressed as Emax and pD2 for acetylcholine (10(-3)-10(-8) m, Ach), bethanechol (10(-3)-10(-8) m) and potassium (10-80 × 10(-3) m, K... |
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Structural and functional cardiac cholinergic deficits in adult neurturin knockout mice.
Cardiovasc. Res. 82 , 93-9, (2009) Previous work provided indirect evidence that the neurotrophic factor neurturin (NRTN) is required for normal cholinergic innervation of the heart. This study used nrtn knockout (KO) and wild-type (WT) mice to determine the effect of nrtn deletion on cardiac ... |
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Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS.
Am. J. Physiol. Gastrointest. Liver Physiol. 303 , G713-722, (2012) Because of its critical importance in rectoanal incontinence, we determined the feasibility to reconstruct internal anal sphincter (IAS) from human IAS smooth muscle cells (SMCs) with functional and molecular attributes similar to the intact sphincter. The re... |
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In vitro effect of bethanechol and suberyldicholine on regions of guinea pig esophagus.
J. Surg. Res. 174(1) , 56-61, (2012) Tissue engineering and regenerative medicine is envisaged as the future option for esophageal replacement; however, engineering of a functional esophagus is impeded by the limited understanding of the anatomical complexity of this dynamic muscular organ. The ... |
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Anti-ulcerogenic mechanisms of the sesquiterpene lactone onopordopicrin-enriched fraction from Arctium lappa L. (Asteraceae): role of somatostatin, gastrin, and endogenous sulfhydryls and nitric oxide.
J. Med. Food 15(4) , 378-83, (2012) Arctium lappa L. has been used in folk medicine as a diuretic, depurative, and digestive stimulant and in dermatological conditions. The mechanisms involved in the anti-ulcerogenic activity of the sesquiterpene onopordopicrin (ONP)-enriched fraction (termed t... |
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Electroacupuncture improves rectal distension-induced delay in solid gastric emptying in dogs.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 301(2) , R465-72, (2011) The aim of this study was to investigate the effects and mechanisms of electroacupuncture (EA) on rectal distension (RD)-induced delay in solid gastric emptying in dogs. Gastric emptying of solids was assessed in 12 dogs chronically implanted with a duodenal ... |
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Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle.
Age (Dordr.) 34(4) , 881-93, (2012) Calcium sensitization is an important physiological process in agonist-induced contraction of smooth muscle. In brief, calcium sensitization is a pathway that leads to smooth muscle contraction independently of changes in [Ca(2+)](i) by mean of inhibition of ... |