4-Fluorophenacyl chloride
4-Fluorophenacyl chloride structure
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Common Name | 4-Fluorophenacyl chloride | ||
|---|---|---|---|---|
| CAS Number | 456-04-2 | Molecular Weight | 172.584 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 247.0±15.0 °C at 760 mmHg | |
| Molecular Formula | C8H6ClFO | Melting Point | 47-50 °C(lit.) | |
| MSDS | USA | Flash Point | 103.2±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones.
Chem. Res. Toxicol. 20(1) , 149-54, (2007) S-(Phenacyl)glutathione reductase (SPG-R) plays a significant role in the biotransformation of reactive alpha-haloketones to nontoxic acetophenones. Comparison of the apparent subunit size, amino acid composition, and catalysis of the reduction of S-(phenacyl... |
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Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.
Bioorg. Med. Chem. 17(4) , 1716-23, (2009) Arylcycloalkylamines, such as phenyl piperidines and piperazines and their arylalkyl substituents, constitute pharmacophoric groups exemplified in several antipsychotic agents. A review of previous reports indicates that arylalkyl substituents can improve the... |
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Allergic contact dermatitis from 3-(alpha-methoxy) methylenebenzofuran-2(3H)-one (MBF) and alpha-chloro-4-fluoroacetophenone (CFAP) in chemical process workers.
Contact Dermatitis 34(6) , 434-5, (1996)
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2, 4, 5-Triarylimidazole inhibitors of IL-1 biosynthesis. Gallagher TF, et al.
Bioorg. Med. Chem. Lett. 5(11) , 1171-1176, (1995)
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