ar-Turmerone
ar-Turmerone structure
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Common Name | ar-Turmerone | ||
|---|---|---|---|---|
| CAS Number | 532-65-0 | Molecular Weight | 216.31900 | |
| Density | N/A | Boiling Point | 326℃ | |
| Molecular Formula | C15H20O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.
Int. J. Food Sci. Nutr. 63(7) , 832-4, (2012) Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes w... |
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Selective induction of apoptosis by ar-turmerone isolated from turmeric (Curcuma longa L) in two human leukemia cell lines, but not in human stomach cancer cell line.
Int. J. Mol. Med. 9(5) , 481-4, (2002) We have investigated the effects of ar-turmerone isolated from turmeric (Curcuma longa L) on DNA of human leukemia cell lines, Molt 4B, HL-60 and stomach cancer KATO III cells. It was found that selective induction of apoptosis by ar-turmerone was observed in... |
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Induction of apoptosis by ar-turmerone on various cell lines.
Int. J. Mol. Med. 14(2) , 253-6, (2004) This study investigated the cytotoxic effect of ar-turmerone isolated from turmeric (Curcuma longa L) on the K562, L1210, U937 and RBL-2H3 cell lines by the MTT assay. Ar-turmerone exhibited potent cytotoxicity on these cancer cell lines. The IC50 values of a... |
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Sesquiterpenoids from the rhizome of Curcuma zedoaria.
Arch. Pharm. Res. 24(5) , 424-6, (2001) In the course of searching for biologically active sesquiterpenoids from Curcuma genus, two sesquiterpenoids were isolated from the rhizome of Curcuma zedoaria (Zingiberaceae). Their structures were identified as ar-turmerone (1) and beta-turmerone (2). The s... |
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Activation of apoptotic protein in U937 cells by a component of turmeric oil.
BMB Rep. 42(2) , 96-100, (2009) Aromatic (ar)-turmerone from turmeric oil displays anti-tumorigenesis activity that includes inhibited cell proliferation. This study investigated ar-turmerone-mediated apoptotic protein activation in human lymphoma U937 cells. Ar-turmerone treatment inhibite... |
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Aromatic-turmerone's anti-inflammatory effects in microglial cells are mediated by protein kinase A and heme oxygenase-1 signaling.
Neurochem. Int. 61(5) , 767-77, (2012) Despite data supporting an immune-modulating effect of ar-turmerone in vitro, the underlying signaling pathways are largely unknown. Here, we investigated the anti-neuroinflammatory properties of ar-turmerone in LPS-stimulated BV-2 microglial cells. Increased... |
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Comparison of yield, composition, and antioxidant activity of turmeric (Curcuma longa L.) extracts obtained using various techniques.
J. Agric. Food Chem. 51(22) , 6604-11, (2003) Turmeric extracts were obtained from two lots of raw material (M and S) using various techniques: hydrodistillation, low pressure solvent extraction, Soxhlet, and supercritical extraction using carbon dioxide and cosolvents. The solvents and cosolvents tested... |
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Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR).
Hum. Vaccin. Immunother. 8(10) , 1416-24, (2012) The aim of this work is to evaluate the effects of purified aromatic-turmerone (ar-turmerione, AR) on murine dendritic cells (DCs). These impacts of AR on DCs from bone marrow derived DCs(BMDCs) were assessed with use of conventional scanning electron microsc... |
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Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa.
Food Chem. Toxicol. 48(8-9) , 2011-20, (2010) The rhizome of Curcuma longa (CL) has been commonly used in Asia as a potential candidate for the treatment of different diseases, including inflammatory disorders and cancers. The present study evaluated the anti-proliferative activities of the isolated comp... |
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Antiplatelet property of Curcuma longa L. rhizome-derived ar-turmerone.
Bioresour. Technol. 97(12) , 1372-6, (2006) The antiplatelet activities of Curcuma longa L. rhizome-derived materials were measured using a platelet aggregometer and compared with those of aspirin as antiplatelet agent. The active constituent from the rhizome of Curcuma longa L. was isolated and charac... |