Bucladesine钙盐

• 常用名: Bucladesine钙盐
• 英文名: Bucladesine (calcium salt)
• CAS号: 938448-87-4
• 分子量: 488.42
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₂₃Ca_0.5N₅O₈P
• 熔点: N/A
• 闪点: N/A

Bucladesine钙盐用途

Bucladesine钙盐(DC2797钙盐)是PKA选择性且细胞可通透激动剂。

Bucladesine钙盐名称

• 中文名: Bucladesine钙盐
• 英文名: Bucladesine calcium salt

Bucladesine钙盐生物活性

• 描述: Bucladesine钙盐(DC2797钙盐)是PKA选择性且细胞可通透激动剂。
• 相关类别:
  信号通路 >> 蛋白酪氨酸激酶 >> PKA
  信号通路 >> 干细胞及 Wnt 通路 >> PKA
  研究领域 >> 其他
• 参考文献:

  [1]. Sharifzadeh, M., et al., Post-training intrahippocampal infusion of nicotine-bucladesine combination causes a synergistic enhancement effect on spatial memory retention in rats. Eur J Pharmacol, 2007. 562(3): p. 212-20.

  [2]. Azami, K., et al., The quantitative evaluation of cholinergic markers in spatial memory improvement induced by nicotine-bucladesine combination in rats. Eur J Pharmacol, 2010. 636(1-3): p. 102-7.

  [3]. Mafune, E., M. Takahashi, and N. Takasugi, Effect of vehicles on percutaneous absorption of bucladesine (dibutyryl cyclic AMP) in normal and damaged rat skin. Biol Pharm Bull, 1995. 18(11): p. 1539-43.

  [4]. Rundfeldt, C., et al., The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), is active in a model of acute skin inflammation. Arch Dermatol Res, 2012.

Bucladesine钙盐物理化学性质

• 分子式: C₁₈H₂₃Ca_0.5N₅O₈P
• 分子量: 488.42
• InChIKey: RCFZVVHQICKFQW-NGVPHMJWSA-L
• SMILES: CCCC(=O)Nc1ncnc2c1ncn2C1OC2COP(=O)([O-])OC2C1OC(=O)CCC.CCCC(=O)Nc1ncnc2c1ncn2C1OC2COP(=O)([O-])OC2C1OC(=O)CCC.[Ca+2]
• 储存条件: 2-8℃

Bucladesine钙盐英文别名

• Butanoic acid, (4aR,6R,7R,7aR)-tetrahydro-2-hydroxy-2-oxido-6-[6-[(1-oxobutyl)amino]-9H-purin-9-yl]-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-7-yl ester, calcium salt (2:1)
• (4aR,6R,7R,7aR)-6-[6-(Butyrylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butanoate - calcium (2:1)
• Bucladesine (calcium salt)