Piriprost potassium salt

• 常用名: Piriprost potassium salt
• 英文名: U 60257B
• CAS号: 88851-62-1
• 分子量: 463.65
• 密度: N/A
• 沸点: 618.6ºC at 760 mmHg
• 分子式: C₂₆H₃₄KNO₄
• 熔点: N/A
• 闪点: 327.9ºC

Piriprost potassium salt用途

Piriprost (U-60,257B) potassium 是一种白三烯 (leukotriene) 合成抑制剂。Piriprost potassium 抑制猪肺细胞白三烯和组胺的释放,其 IC50 为 0.11 μM。Piriprost potassium 增加培养的子宫内膜基质细胞碱性磷酸酶 (ALP) 活性。

Piriprost potassium salt名称

• 中文名: 吡前列素(钾盐)
• 英文名: piriprost potassium salt

Piriprost potassium salt生物活性

• 描述: Piriprost (U-60,257B) potassium 是一种白三烯 (leukotriene) 合成抑制剂。Piriprost potassium 抑制猪肺细胞白三烯和组胺的释放,其 IC50 为 0.11 μM。Piriprost potassium 增加培养的子宫内膜基质细胞碱性磷酸酶 (ALP) 活性。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 白三烯受体
  研究领域 >> 炎症/免疫
• 靶点:

  IC50: 0.11 μM (leukotriene)[2]

• 参考文献:

  [1]. Cejic SS, Kennedy TG. Examination of the effects of piriprost (U-60,257B) on alkaline phosphatase activity of rat endometrial stromal cells in vitro. Prostaglandins. 1991 Aug;42(2):179-89.

  [2]. McCormack DG, Paterson NA. The contrasting influence of two lipoxygenase inhibitors on hypoxic pulmonary vasoconstriction in anesthetized pigs. Am Rev Respir Dis. 1989 Jan;139(1):100-5.

Piriprost potassium salt物理化学性质

• 沸点: 618.6ºC at 760 mmHg
• 分子式: C₂₆H₃₄KNO₄
• 分子量: 463.65
• 闪点: 327.9ºC
• 精确质量: 463.212494
• PSA: 85.52000
• LogP: 3.43800
• 储存条件: -20°C，密闭，干燥

Piriprost potassium saltMSDS

Piriprost potassium saltMSDS英文版

Piriprost potassium salt安全信息

• 安全声明 (欧洲): 22-24/25

Piriprost potassium salt英文别名

• Cyclopenta[b]pyrrole-2-pentanoic acid, 1,4,5,6-tetrahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octen-1-yl]-1-phenyl-, potassium salt, (4R,5R)- (1:1)
• [4R-[4a(1E,3S*),5b]]-1,4,5,6-Tetrahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)-1-phenylcyclopenta[b]pyrrole-2-pentanoic Acid Monopotassium Salt
• u60,257b potassium salt
• Potassium (4R,5R)-1,4,5,6-Tetrahydro-5-hydroxy-4-[(E)-(3S)-3-hydroxy-1-octenyl]-1-phenylcyclopenta[b]pyrrole-2-valerate
• Potassium 5-{(4R,5R)-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octen-1-yl]-1-phenyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrol-2-yl}pentanoate
• U 60257B