吡咯烷四磷酸

更新时间：2025-08-25 19:52:46

吡咯烷四磷酸结构式	常用名	吡咯烷四磷酸	英文名	Pyronaridine tetraphosphate
	CAS号	76748-86-2	分子量	910.030
	密度	1.357g/cm3	沸点	657.2ºC at 760 mmHg
	分子式	C₂₉H₄₄ClN₅O₁₈P₄	熔点	233-236° (dec)
	MSDS	中文版美版	闪点	351.3ºC
	符号	GHS07, GHS08	信号词	Warning

吡咯烷四磷酸用途

Pyronaridine tetraphosphate 是一种含甘露醇的抗疟疾药物,对耐药的镰状疟原虫,间日疟原虫, 卵形疟原虫和三日疟原虫均具有良好的疗效。

中文名	4-[(7-氯-2-甲氧基-1,5-二氢吡啶并[3,2-b]喹啉-10-基)亚氨]-2,6-二(吡咯烷-1-基甲基)环己-2,5-二烯-1-酮磷酸盐 (1:4)
英文名	4-[(7-chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one,phosphoric acid
英文别名	更多

描述	Pyronaridine tetraphosphate 是一种含甘露醇的抗疟疾药物,对耐药的镰状疟原虫,间日疟原虫, 卵形疟原虫和三日疟原虫均具有良好的疗效。
相关类别	信号通路 >> 其他 >> 其他研究领域 >> 感染
参考文献	[1]. Vivas L, et al. Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta Trop. 2008 Mar;105(3):222-8.

密度	1.357g/cm3
沸点	657.2ºC at 760 mmHg
熔点	233-236° (dec)
分子式	C₂₉H₄₄ClN₅O₁₈P₄
分子量	910.030
闪点	351.3ºC
精确质量	909.132019
PSA	424.03000
LogP	2.32020
InChIKey	YKUQEKXHQFYULM-UHFFFAOYSA-N
SMILES	COc1ccc2nc3cc(Cl)ccc3c(Nc3cc(CN4CCCC4)c(O)c(CN4CCCC4)c3)c2n1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
折射率	1.72
储存条件	2-8°C
水溶解性	acetic acid: soluble5mg/mL

吡咯烷四磷酸毒性英文版

符号	GHS07, GHS08
信号词	Warning
危害声明	H302-H361
警示性声明	P280-P301 + P312 + P330
个人防护装备	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
危害码 (欧洲)	Xn
风险声明 (欧洲)	63-22-41
安全声明 (欧洲)	26-36/37-39
危险品运输编码	NONH for all modes of transport
RTECS号	SK4920000

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Pyronaridine phosphate

Phenol,4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)-,phosphate (1:4)

Pyronaridine Tetraphosphate

UNII-2T289F9ACO

4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4)

Phenol, 4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)-, phosphate (1:4) (salt)

Pyranoridine phosphate