双去甲氧基姜黄素

更新时间：2024-01-04 20:50:55

双去甲氧基姜黄素结构式	常用名	双去甲氧基姜黄素	英文名	Bisdemethoxycurcumin
	CAS号	33171-05-0	分子量	308.328
	密度	1.3±0.1 g/cm3	沸点	551.3±45.0 °C at 760 mmHg
	分子式	C₁₉H₁₆O₄	熔点	221-223ºC
	MSDS	中文版美版	闪点	301.3±25.2 °C

双去甲氧基姜黄素用途

双去甲氧基姜黄素(Bisdemethoxycurcumin)是姜黄素衍生物,具有抗炎症和抗癌活性。

中文名	双去甲氧基姜黄素
英文名	Bisdemethoxycurcumin
中文别名	双去氧基姜黄素 \| 姜黄素III
英文别名	更多

描述	双去甲氧基姜黄素(Bisdemethoxycurcumin)是姜黄素衍生物,具有抗炎症和抗癌活性。
相关类别	信号通路 >> 细胞凋亡 >> 细胞凋亡信号通路 >> 自噬 >> 自噬天然产物 >> 酚类研究领域 >> 癌症
参考文献	[1]. Lee PJ, et al. Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2. Molecules. 2015 Jan 14;20(1):1277-92. [2]. Chen J, et al. Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. Food Funct. 2014 Dec 24. [3]. Luo C, et al. Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction. Oncol Lett. 2015 Jan;9(1):270-274. [4]. Li YB, et al. Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evid Based Complement Alternat Med. 2013;2013:851714.

描述

双去甲氧基姜黄素(Bisdemethoxycurcumin)是姜黄素衍生物,具有抗炎症和抗癌活性。

相关类别

信号通路 >> 细胞凋亡 >> 细胞凋亡

信号通路 >> 自噬 >> 自噬

天然产物 >> 酚类

研究领域 >> 癌症

参考文献

[1]. Lee PJ, et al. Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2. Molecules. 2015 Jan 14;20(1):1277-92.

[2]. Chen J, et al. Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. Food Funct. 2014 Dec 24.

[3]. Luo C, et al. Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction. Oncol Lett. 2015 Jan;9(1):270-274.

[4]. Li YB, et al. Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evid Based Complement Alternat Med. 2013;2013:851714.

密度	1.3±0.1 g/cm3
沸点	551.3±45.0 °C at 760 mmHg
熔点	221-223ºC
分子式	C₁₉H₁₆O₄
分子量	308.328
闪点	301.3±25.2 °C
精确质量	308.104858
PSA	74.60000
LogP	3.39
蒸汽压	0.0±1.5 mmHg at 25°C
折射率	1.680
储存条件	-20°C

危险品运输编码	NONH for all modes of transport

An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

J. Nat. Prod. 73 , 1193-5, (2010)

Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple fo...

Molecularly imprinted polymers for cleanup and selective extraction of curcuminoids in medicinal herbal extracts.

Anal. Bioanal. Chem 407(3) , 803-12, (2015)

This paper describes the synthesis of novel molecularly imprinted polymers (MIPs), prepared by a noncovalent imprinting approach, for cleanup and preconcentration of curcumin (CUR) and bisdemethoxycur...

Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity.

Eur. J. Med. Chem. 45 , 4446-57, (2010)

Curcumin (1), demethoxycurcumin (2) and bisdemethoxycurcumin (3), the curcuminoid constituents of the medicinal plant Curcuma longa L., have been structurally modified to 55 analogs and antimycobacter...

1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)-

bis(4-hydroxycinnamoyl)methane

Bis(p-hydroxycinnamoyl)methane

Bisdemethoxycurcumin

(1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

(1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione

1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-