溴代甲基阿托品结构式
|
常用名 | 溴代甲基阿托品 | 英文名 | atropine methyl bromide |
|---|---|---|---|---|
| CAS号 | 2870-71-5 | 分子量 | 384.31 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H26BrNO3 | 熔点 | 222-223° | |
| MSDS | N/A | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
溴代甲基阿托品用途Atropine methyl bromide, 是毒蕈碱型受体 (mAChR) 的拮抗剂,是阿托品的季铵盐,是眼科检查时用于瞳孔扩张的药物。由于其高度极性,被用于缓解婴儿幽门痉挛。它比阿托品更不易进入中枢神经系统。 |
| 中文名 | 溴代甲基阿托品 |
|---|---|
| 英文名 | (8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate,bromide |
| 中文别名 | 溴甲阿托品 | 阿托品甲基溴化物 |
| 英文别名 | 更多 |
| 描述 | Atropine methyl bromide, 是毒蕈碱型受体 (mAChR) 的拮抗剂,是阿托品的季铵盐,是眼科检查时用于瞳孔扩张的药物。由于其高度极性,被用于缓解婴儿幽门痉挛。它比阿托品更不易进入中枢神经系统。 |
|---|---|
| 相关类别 | |
| 参考文献 |
[1]. Methylatropine. |
| 熔点 | 222-223° |
|---|---|
| 分子式 | C18H26BrNO3 |
| 分子量 | 384.31 |
| 精确质量 | 383.11000 |
| PSA | 46.53000 |
| 外观性状 | neat |
| 储存条件 | 2-8℃ |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:1 3.氢键受体数量:4 4.可旋转化学键数量:5 5.互变异构体数量:无 6.拓扑分子极性表面积:46.5 7.重原子数量:23 8.表面电荷:0 9.复杂度:387 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:3 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:2 |
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溴代甲基阿托品 2870-71-5 |
| 文献：Malpass American Journal of Pharmacy and the Sciences Supporting Public Health (1937-1978), 1951 , vol. 123, p. 5,8 |
| 溴代甲基阿托品上游产品 2 | |
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| 溴代甲基阿托品下游产品 0 | |
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Bezold–Jarisch reflex in sino-aortic denervated malnourished rats
Auton. Neurosci. 162(1-2) , 48-53, (2011) In this study we assessed the role of Bezold–Jarisch reflex (BJR) in the regulation of blood pressure (BP) of malnourished (MN) and control rats (CN) with sino-aortic denervation (SAD). Fischer rats w... |
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Frequency components of systolic blood pressure variability reflect vasomotor and cardiac sympathetic functions in conscious rats.
J. Physiol. Sci. 61(5) , 373-83, (2011) In this study, after confirming the suppression of autonomic nervous function by isoflurane anesthesia using autonomic antagonists, we pharmacologically investigated the involvement of vasomotor and c... |
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Central and peripheral mechanisms underlying gastric distention inhibitory reflex responses in hypercapnic-acidotic rats.
Am. J. Physiol. Heart Circ. Physiol. 300(3) , H1003-12, (2011) We have observed that in chloralose-anesthetized animals, gastric distension (GD) typically increases blood pressure (BP) under normoxic normocapnic conditions. However, we recently noted repeatable d... |
| Hyoscyamine methylbromide |
| EINECS 220-700-1 |
| 8-Methylatropinium bromide |
| Methylatropine bromide |
| Mintussin |
| Methylatropinium bromide |
| Atropine methobromide |
| atropine methyl bromohydrate |
| 8,8-dimethyl-3endo-DL-tropoyloxy-nortropanium,bromide |
| MFCD00050293 |
| ATROPINE METHYL BROMIDE |
| Tropin |
| Mydriasin |
| N-Methylatropine bromide |
| 8,8-Dimethyl-3endo-DL-tropoyloxy-nortropanium,Bromid |
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