10,11-Dehydrocurvularin

• 常用名: 10,11-Dehydrocurvularin
• 英文名: 10,11-Dehydrocurvularin
• CAS号: 21178-57-4
• 分子量: 290.31100
• 密度: 1.225 g/cm3
• 沸点: 576.3ºC at 760 mm
• 分子式: C₁₆H₁₈O₅
• 熔点: N/A
• 闪点: 216.7ºC

10,11-Dehydrocurvularin用途

10,11-Dehydrocurvularin 是一种常见的真菌毒素和抗生素。10,11-Dehydrocurvularin 是热休克反应的强激活剂。10,11-Dehydrocurvularin 抑制 TGF-β 信号通路。抗肿瘤活性

10,11-Dehydrocurvularin名称

• 中文名: 10,11-dehydro Curvularin
• 英文名: (5S,9E)-13,15-dihydroxy-5-methyl-4-oxabicyclo[10.4.0]hexadeca-1(12),9,13,15-tetraene-3,11-dione

10,11-Dehydrocurvularin生物活性

• 描述: 10,11-Dehydrocurvularin 是一种常见的真菌毒素和抗生素。10,11-Dehydrocurvularin 是热休克反应的强激活剂。10,11-Dehydrocurvularin 抑制 TGF-β 信号通路。抗肿瘤活性
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 干细胞及 Wnt 通路 >> TGF-β/Smad蛋白
  信号通路 >> 代谢酶/蛋白酶 >> HSP
  信号通路 >> TGF-beta/Smad 信号通路 >> TGF-β/Smad蛋白
  研究领域 >> 感染
  信号通路 >> 细胞周期/DNA损伤 >> HSP
• 参考文献:

  [1]. Xu Y, et al. Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol. 2013 Mar;79(6):2038-47.

  [2]. Cochrane RV, et al. Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs. Chembiochem. 2015 Nov;16(17):2479-83.

10,11-Dehydrocurvularin物理化学性质

• 密度: 1.225 g/cm3
• 沸点: 576.3ºC at 760 mm
• 分子式: C₁₆H₁₈O₅
• 分子量: 290.31100
• 闪点: 216.7ºC
• 精确质量: 290.11500
• PSA: 83.83000
• LogP: 2.49480
• 蒸汽压: 7.02E-14mmHg at 25°C
• 折射率: 1.555
• 储存条件: -20°C，密闭，干燥

10,11-Dehydrocurvularin安全信息

• 海关编码: 2932999099

10,11-Dehydrocurvularin海关

• 海关编码: 2932999099
• 中文概述: 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

10,11-Dehydrocurvularin英文别名

• trans-dehydrocurvularin
• E-dehydrocurvularin
• 10,11-dehydrocurvularin
• 8-dehydrocurvularin
• Dehydrocurvularin
• AmbotzLS-1091