Miglustat盐酸盐

• 常用名: Miglustat盐酸盐
• 英文名: Miglustat hydrochloride
• CAS号: 210110-90-0
• 分子量: 255.739
• 密度: N/A
• 沸点: 421.2ºC at 760 mmHg
• 分子式: C₁₀H₂₂ClNO₄
• 熔点: 169-172ºC
• 闪点: 208.5ºC

Miglustat盐酸盐用途

Miglustat盐酸盐是葡萄糖神经酰胺合成酶抑制剂,可作用于I型戈谢病。

Miglustat盐酸盐名称

• 中文名: Miglustat盐酸盐
• 英文名: N-Butyldeoxynojirimycin Hydrochloride

Miglustat盐酸盐生物活性

• 描述: Miglustat盐酸盐是葡萄糖神经酰胺合成酶抑制剂,可作用于I型戈谢病。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7.

  [2]. van Giersbergen, P.L. and J. Dingemanse, Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase. J Clin Pharmacol, 2007. 47(10): p. 1277-82.

Miglustat盐酸盐物理化学性质

• 沸点: 421.2ºC at 760 mmHg
• 熔点: 169-172ºC
• 分子式: C₁₀H₂₂ClNO₄
• 分子量: 255.739
• 闪点: 208.5ºC
• 精确质量: 255.123734
• PSA: 84.16000
• 蒸汽压: 7.37E-09mmHg at 25°C
• 储存条件: 2-8℃

Miglustat盐酸盐安全信息

• 危害码 (欧洲): Xi

Miglustat盐酸盐英文别名

• Hydrogen chloride (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol (1:1:1)
• (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride (1:1)
• 3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, chloride, hydrogen salt, (2R,3R,4R,5S)- (1:1)
• Miglustat hydrochloride,(2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriolhydrochloride
• Miglustat (hydrochloride)