薯蓣皂甙；薯蓣皂苷

• 常用名: 薯蓣皂甙；薯蓣皂苷
• 英文名: Dioscin
• CAS号: 19057-60-4
• 分子量: 869.044
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₄₅H₇₂O₁₆
• 熔点: 294-296 ℃
• 闪点: N/A

薯蓣皂甙；薯蓣皂苷用途

Dioscin(CCRIS 4123; Collettiside III)是天然的植物来源的甾体皂苷,针对多种癌细胞有较好的抗癌活性。

薯蓣皂甙；薯蓣皂苷名称

• 中文名: 薯蓣皂苷
• 英文名: dioscin
• 中文别名: 薯蓣皂甙 | 重楼皂苷III

薯蓣皂甙；薯蓣皂苷生物活性

• 描述: Dioscin(CCRIS 4123; Collettiside III)是天然的植物来源的甾体皂苷,针对多种癌细胞有较好的抗癌活性。
• 相关类别:
  信号通路 >> 自噬 >> 自噬
  研究领域 >> 癌症
  天然产物 >> 类固醇
• 参考文献:

  [1]. Chen J, et al. Dioscin-induced apoptosis of human LNCaP prostate carcinoma cells through activation of caspase-3 and modulation of Bcl-2 protein family. J Huazhong Univ Sci Technolog Med Sci. 2014 Feb;34(1):125-30.

  [2]. Qu X, et al. Dioscin inhibits osteoclast differentiation and bone resorption though down-regulating the Akt signaling cascades. Biochem Biophys Res Commun. 2014 Jan 10;443(2):658-65.

  [3]. Qin J, et al. Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cells. Drug Res (Stuttg). 2014 Jan;64(1):47-52.

薯蓣皂甙；薯蓣皂苷物理化学性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 294-296 ℃
• 分子式: C₄₅H₇₂O₁₆
• 分子量: 869.044
• 精确质量: 868.482056
• PSA: 235.68000
• LogP: 7.24
• InChIKey: VNONINPVFQTJOC-ZGXDEBHDSA-N
• SMILES: CC1CCC2(OC1)OC1CC3C4CC=C5CC(OC6OC(CO)C(OC7OC(C)C(O)C(O)C7O)C(O)C6OC6OC(C)C(O)C(O)C6O)CCC5(C)C4CCC3(C)C1C2C
• 折射率: 1.614
• 储存条件: 室温

薯蓣皂甙；薯蓣皂苷毒性和生态

薯蓣皂甙；薯蓣皂苷安全信息

• 危害码 (欧洲): Xi
• 安全声明 (欧洲): 24/25
• 海关编码: 29389090

薯蓣皂甙；薯蓣皂苷英文别名

• (3β,25R)-Spirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->4)]-β-D-glucopyranoside
• collettisideiii
• (25R)-Spirost-5-en-3b-yl O-6-Deoxy-a-L-mannopyranosyl-(1®2)-O-[6-deoxy-a-L-mannopyranosyl-(1®4)]-b-D-glucopyranoside
• β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[6-deoxy-α-L-mannopyranosyl-(1->4)]-
• Dioscin
• polyphyllin III
• Diosgenin Bis-a-L-rhamnopyranosyl-(1®2 And 1®4)-b-D-Glucopyranoside