醋酸戈舍瑞林

更新时间:2019-06-10 18:39:14

醋酸戈舍瑞林结构式
醋酸戈舍瑞林结构式
常用名 醋酸戈舍瑞林 英文名 Goserelin Acetate
CAS号 145781-92-6 分子量 1329.46
密度 1.5±0.1 g/cm3 沸点 1695.5ºC at 760mmHg
分子式 C61H88N18O16 熔点 >190°C (dec.)
MSDS 中文版 美版 闪点 N/A
符号 GHS08
GHS08
信号词 Danger

 醋酸戈舍瑞林用途


Goserelin (ICI 118630)乙酸盐是GnRH激动剂。

 醋酸戈舍瑞林名称

中文名 醋酸戈舍瑞林
英文名 Goserelin Acetate
英文别名 更多

 醋酸戈舍瑞林生物活性

描述 Goserelin (ICI 118630)乙酸盐是GnRH激动剂。
相关类别

 醋酸戈舍瑞林物理化学性质

密度 1.5±0.1 g/cm3
沸点 1695.5ºC at 760mmHg
熔点 >190°C (dec.)
分子式 C61H88N18O16
分子量 1329.46
PSA 493.39000
LogP -0.95
外观性状 白色结晶粉末
蒸汽压 0mmHg at 25°C
折射率 1.692
储存条件 −20°C
水溶解性 H2O: 20 mg/mL, clear, colorless

 醋酸戈舍瑞林安全信息

符号 GHS08
GHS08
信号词 Danger
危害声明 H360
警示性声明 P201-P280-P308 + P313
个人防护装备 Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲) 22-24/25
危险品运输编码 NONH for all modes of transport
WGK德国 3
RTECS号 OK6369800

 醋酸戈舍瑞林文献10

更多文献
Stability of peptide drugs in the colon.

Eur. J. Pharm. Sci. 78 , 31-6, (2015)

This study was the first to investigate the colonic stability of 17 peptide molecules (insulin, calcitonin, glucagon, secretin, somatostatin, desmopressin, oxytocin, Arg-vasopressin, octreotide, ciclo...

Targeted gold nanoparticles enhance sensitization of prostate tumors to megavoltage radiation therapy in vivo.

Nanomedicine: Nanotechnology, Biology, and Medicine 11 , 1277-83, (2015)

We report potent radiosensitization of prostate cancers in vitro and in vivo using goserelin-conjugated gold nanorods. Progressive receptor-mediated internalization of conjugated nanorods over time in...

Toward oral delivery of biopharmaceuticals: an assessment of the gastrointestinal stability of 17 peptide drugs.

Mol. Pharm. 12(3) , 966-73, (2015)

A major barrier to successful oral delivery of peptide and protein molecules is their inherent instability in the lumen of the gastrointestinal tract. The aim of this study was to determine the stabil...

 醋酸戈舍瑞林英文别名

Goserelin acetate
Goserelin acetate [D-Ser(tBu)6,Azagly10]-LHRH acetate salt
Goserelin (acetate)
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醋酸戈舍瑞林生产厂家


参考价格:$193/10mM*1mLinDMSO

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