(D-Ser(tBu)6,AzaGly10)-LHRH acetate salt

Modify Date: 2024-01-02 02:35:58

(D-Ser(tBu)6,AzaGly10)-LHRH acetate salt structure	Common Name	(D-Ser(tBu)6,AzaGly10)-LHRH acetate salt
	CAS Number	145781-92-6	Molecular Weight	1329.46
	Density	1.5±0.1 g/cm3	Boiling Point	1695.5ºC at 760mmHg
	Molecular Formula	C₆₁H₈₈N₁₈O₁₆	Melting Point	>190°C (dec.)
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Danger

Use of (D-Ser(tBu)6,AzaGly10)-LHRH acetate salt

Goserelin (ICI 118630) acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).IC50 value:Target: GnRH agonistGoserelin is used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transsexuals and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot. Goserelin stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner.

Name	Goserelin Acetate
Synonym	More Synonyms

Description	Goserelin (ICI 118630) acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).IC50 value:Target: GnRH agonistGoserelin is used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transsexuals and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot. Goserelin stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Endocrinology

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Endocrinology

Density	1.5±0.1 g/cm3
Boiling Point	1695.5ºC at 760mmHg
Melting Point	>190°C (dec.)
Molecular Formula	C₆₁H₈₈N₁₈O₁₆
Molecular Weight	1329.46
PSA	493.39000
LogP	-0.95
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.692
Storage condition	−20°C
Water Solubility	H2O: 20 mg/mL, clear, colorless

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H360
Precautionary Statements	P201-P280-P308 + P313
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	OK6369800

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Goserelin acetate

Goserelin acetate [D-Ser(tBu)6,Azagly10]-LHRH acetate salt

Goserelin (acetate)