7054-11-7

• 常用中文名：N,N-二甲基-γ-(4-氯苯基)-2-吡啶丙胺顺丁烯二酸盐
• 常用英文名：CHLORPHENAMINE MALEATES
• CAS号：7054-11-7
• 分子式：C₂₀H₂₃ClN₂O₄
• 分子量：390.86100
• 发布时间：2018-12-30 15:05:39
• 更新时间：2024-01-04 16:31:44

名称

• 中文名: N,N-二甲基-γ-(4-氯苯基)-2-吡啶丙胺顺丁烯二酸盐
• 英文名: chlorpheniramine maleate
• 中文别名: 氯苯吡胺马来酸盐
• 英文别名: chlorphenamine maleate; chloropheniramine maleate; chlortrimeton

物化性质

• 熔点: 130-135ºC(lit.)
• 分子式: C₂₀H₂₃ClN₂O₄
• 分子量: 390.86100
• 精确质量: 390.13500
• PSA: 90.73000
• LogP: 3.14170
• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：390.134635 Da

  8、标称质量：390 Da

  9、平均质量：390.8606 Da

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US6503000 CAS REGISTRY NUMBER : 7054-11-7 LAST UPDATED : 199806 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C16-H19-Cl-N2.C4-H4-O4 MOLECULAR WEIGHT : 390.90 WISWESSER LINE NOTATION : T6NJ BYR DG&2N1&1 &QV1U1VQ -+- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 118 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 89 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 121 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 73 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 265 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 500 umol/L REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 24,181,1994

安全

• 危害码 (欧洲): T,Xi
• 风险声明 (欧洲): 25-36/37/38
• 安全声明 (欧洲): 36/37/39-45-36-26
• 危险品运输编码: UN 2811 6.1/PG 3