56225-81-1

• 常用中文名：N,N-二甲基-Γ-[4-三氟甲基苯氧基]苯丙胺
• 常用英文名：3-(4-(Trifluoromethyl)phenoxy)-N,N-dimethyl-3-phenylpropan-1-amine
• CAS号：56225-81-1
• 分子式：C₁₈H₂₀F₃NO
• 分子量：323.35300
• 发布时间：2019-01-21 07:28:50
• 更新时间：2025-08-22 05:13:51

名称

• 中文名: 3-(4-(三氟甲基)苯氧基)-N,N-二甲基-3-苯基丙-1-胺
• 英文名: N,N-dimethyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
• 中文别名: N,N-二甲基-Γ-[4-三氟甲基苯氧基]苯丙胺; N,N-二甲基-GAMMA-[4-三氟甲基苯氧基]苯丙胺
• 英文别名: N-methyl fluoxetine; 3-(4-(TRIFLUOROMETHYL)PHENOXY)-N,N-DIMETHYL-3-PHENYLPROPAN-1-AMINE; N,N-dimethyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)-1-propylamine; N,N-dimethyl-3-(4-trifluoromethyl-phenyloxy)-3-phenyl-propanamine; N,N-dimethyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine; N,N-dimethyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine

物化性质

• 密度: 1.148g/cm3
• 沸点: 388.078ºC at 760 mmHg
• 分子式: C₁₈H₂₀F₃NO
• 分子量: 323.35300
• 闪点: 188.503ºC
• 精确质量: 323.15000
• PSA: 12.47000
• LogP: 4.77720
• 折射率: 1.513

合成路线

402-45-9 1011-59-2 ~% 56225-81-1

文献：Eli Lilly and Company Patent: US4584404 A1, 1986 ; US 4584404 A

1011-59-2 ~% 56225-81-1

文献：Conjuchem, Inc. Patent: US6706892 B1, 2004 ;

124-40-3 81347-68-4 ~% 56225-81-1

文献：Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Gronborg; Koldso, Heidi; Schiott, Birgit; Stromgaard, Kristian; Kristensen, Anders S. Molecular Pharmacology, 2014 , vol. 85, # 5 p. 703 - 714

402-45-9 5554-64-3 ~33% 56225-81-1

文献：O'Brien, Peter; Phillips, David W.; Towers, Timothy D. Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7333 - 7335

402-45-9 40116-79-8 ~33% 56225-81-1

文献：O'Brien, Peter; Phillips, David W.; Towers, Timothy D. Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7333 - 7335

104-52-9 ~% 56225-81-1

文献：Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Gronborg; Koldso, Heidi; Schiott, Birgit; Stromgaard, Kristian; Kristensen, Anders S. Molecular Pharmacology, 2014 , vol. 85, # 5 p. 703 - 714

21763-00-8 ~% 56225-81-1

文献：Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Gronborg; Koldso, Heidi; Schiott, Birgit; Stromgaard, Kristian; Kristensen, Anders S. Molecular Pharmacology, 2014 , vol. 85, # 5 p. 703 - 714

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