117184-53-9

• 常用中文名：芳香松香
• 常用英文名：Aranorosin
• CAS号：117184-53-9
• 分子式：C₂₃H₃₃NO₆
• 分子量：419.51100
• 发布时间：2016-09-29 23:26:57
• 更新时间：2024-01-02 12:18:54
• Aranorosin是一种有效的抗真菌抗生素,已从一株玫瑰假蛛网膜菌的培养滤液和菌丝体中分离出来[1]。

名称

• 中文名: 芳香松香
• 英文名: Aranorosin
• 英文别名: 2,4-Dodecadienamide,N-(dihydro-5'-hydroxy-6-oxospiro(4,8-dioxatricyclo(5.1.0.0(sup 3,5))octane-2,2'(3'H)-furan)-4'-yl)-4,6-dimethyl; 2,4-Dodecadienamide,N-(dihydro-5'-hydroxy-6-oxospiro(4,8-dioxatricyclo(5.1.0.0(3,5))octane-2,2'(3'H)-furan)-4'-yl)-4,6-dimethyl; (6R)-N-((1'R,3'S,5'R,7'S)-5-Hydroxy-6'-oxodihydro-3H-4',8'-dioxaspiro[furan-2,2'-tricyclo[5.1.0.03,5]octan]-4-yl)-4,6-dimethyldodeca-2,4-dienamide

物化性质

• 密度: 1.23g/cm3
• 沸点: 650.4ºC at 760mmHg
• 分子式: C₂₃H₃₃NO₆
• 分子量: 419.51100
• 闪点: 347.2ºC
• 精确质量: 419.23100
• PSA: 100.69000
• LogP: 2.56610
• 蒸汽压: 1.14E-19mmHg at 25°C
• 折射率: 1.565

生物活性

• 描述: Aranorosin是一种有效的抗真菌抗生素,已从一株玫瑰假蛛网膜菌的培养滤液和菌丝体中分离出来[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
• 参考文献:

  [1]. H W Fehlhaber, et al. Aranorosin, a novel antibiotic from Pseudoarachniotus roseus. II. Structure elucidation. J Antibiot (Tokyo). 1988 Dec;41(12):1785-94.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : JR1550000 CHEMICAL NAME : 2,4-Dodecadienamide, N-(dihydro-5'-hydroxy-6-oxospiro(4,8-dioxatricyclo(5. 1.0.0(sup 3,5)) octane-2,2'(3'H)-furan)-4'-yl)-4,6-dimethyl- CAS REGISTRY NUMBER : 117184-53-9 LAST UPDATED : 199312 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H33-N-O6 MOLECULAR WEIGHT : 419.57 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 41,1780,1988