127-25-3

• 常用中文名：松香甲酯(部分氢化)
• 常用英文名：1-Phenanthrenecarboxylicacid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-,methyl ester, (1R,4aR,4bR,10aR)-
• CAS号：127-25-3
• 分子式：C₂₁H₃₂O₂
• 分子量：316.47800
• 相关类别： 食品添加剂 胶姆糖基础剂
• 发布时间：2018-05-23 08:00:00
• 更新时间：2024-01-05 18:06:06

• 胶姆糖咀嚼料。
  

名称

• 中文名: 松香甲酯(部分氢化)
• 英文名: methyl abietate
• 中文别名: 1,4A-二甲基-7-(1-甲基乙基)-1,2,3,4,4A,4B,5,6,10,10A-十氢-1-菲羧酸甲酯; 松香甲酯,部分氢化
• 英文别名: abieticacid,methylester; Methyl rosinate; methyl (-)-abietate; methyl abietadien-19-oate; Abietic acid methyl; ABALYN; woodrosin,methylester; methylesterofwoodrosin; methyl abieta-7,13-dien-18-oate; Methyl resinate; METHYL ESTER OF ROSIN; EINECS 204-832-7; methyl abietadien-18-oate

物化性质

• 密度: 1.02g/cm3
• 沸点: 403.8ºC at 760mmHg
• 分子式: C₂₁H₃₂O₂
• 分子量: 316.47800
• 闪点: 192.8ºC
• 精确质量: 316.24000
• PSA: 26.30000
• LogP: 5.29460
• 蒸汽压: 9.9E-07mmHg at 25°C
• 折射率: 1.521
• 分子结构:

  1、 摩尔折射率：94.322、 摩尔体积（cm³/mol）：309.43、 等张比容（90.2K）：762.44、 表面张力（dyne/cm）：36.85、 极化率（10-24cm3）：37.39

• 更多:

  1.性状：淡琥珀色液态树脂。几乎无臭。

  2.相对密度(d2020)：1.040。

  3.沸点（℃）：360～365(分解)。

  4.溶解性：溶于丙酮和苯，不溶于水。

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TP8590000 CHEMICAL NAME : Podocarpa-7,13-dien-15-oic acid, 13-isopropyl-, methyl ester CAS REGISTRY NUMBER : 127-25-3 BEILSTEIN REFERENCE NO. : 2702228 LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C21-H32-O2 MOLECULAR WEIGHT : 316.53 WISWESSER LINE NOTATION : L B666 EU GUTJ A1 EY1&1 KVO1 K1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,931,1974 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,931,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,931,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83115 No. of Facilities: 2499 (estimated) No. of Industries: 25 No. of Occupations: 26 No. of Employees: 23335 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83115 No. of Facilities: 468 (estimated) No. of Industries: 5 No. of Occupations: 15 No. of Employees: 5251 (estimated) No. of Female Employees: 1791 (estimated)

合成路线

514-10-3 77-78-1 ~99% 127-25-3

文献：Zhou, Bing; Li, Xiaomei; Feng, Huijin; Li, Yuanchao Tetrahedron, 2010 , vol. 66, # 29 p. 5396 - 5401

186581-53-3 514-10-3 ~99% 127-25-3

文献：Dos Santos, Catarina; De Rosso, Cesar R.S.; Imamura, Paulo M. Synthetic Communications, 1999 , vol. 29, # 11 p. 1903 - 1910

67-56-1 514-10-3 ~84% 127-25-3

文献：Morcillo, Sara P.; Alvarez De Cienfuegos, Luis; Mota, Antonio J.; Justicia, Jose; Robles, Rafael Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2277 - 2281

67-71-0 514-10-3 ~84% 127-25-3

文献：Cambie, Richard C.; Rutledge, Peter S.; Ryan, Glen R.; Strange, Gary A.; Woodgate, Paul D. Australian Journal of Chemistry, 1990 , vol. 43, # 5 p. 867 - 881

514-10-3 74-88-4 ~91% 127-25-3

文献：Rafferty, Ryan J.; Hicklin, Robert W.; Maloof, Katherine A.; Hergenrother, Paul J. Angewandte Chemie - International Edition, 2014 , vol. 53, # 1 p. 220 - 224 Angew. Chem., 2014 , vol. 126, # 1 p. 224 - 228,5

67-56-1 19897-44-0 ~49% 127-25-3

文献：Bardyshev Russian Journal of Organic Chemistry, 1999 , vol. 35, # 1 p. 41 - 55

514-10-3 18107-18-1 ~94% 127-25-3

文献：Presser, Armin; Huefner, Antje Monatshefte fur Chemie, 2004 , vol. 135, # 8 p. 1015 - 1022

14351-66-7 ~% 127-25-3

文献：Russian Journal of Organic Chemistry, , vol. 35, # 1 p. 41 - 55

77-78-1 ~% 127-25-3

文献：Chemische Berichte, , vol. 64, p. 2441,2445

上下游产品

上游产品  8
514-10-3 77-78-1 186581-53-3 67-56-1
67-71-0 74-88-4 18107-18-1 14351-66-7
下游产品  7
483-65-8 514-10-3 1235-74-1 55154-40-0
86788-23-0 22565-68-0 13082-81-0

制备

由松香与甲醇酯化后，再经部分氢化，然后用水蒸气汽提法提纯而得。