1782573-67-4

• 常用中文名：RU-SKI43 HCl
• 常用英文名：RU-SKI43 HCl
• CAS号：1782573-67-4
• 分子式：C₂₂H₃₁ClN₂O₂S
• 分子量：423.012
• 发布时间：2021-01-09 10:12:14
• 更新时间：2025-11-25 16:56:15
• RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.

名称

• 英文名: RU-SKI 43 (hydrochloride)
• 英文别名: 2-[(2-Methylbutyl)amino]-1-{4-[(3-methylphenoxy)methyl]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl}ethanone hydrochloride (1:1); MFCD25371547; Ethanone, 1-[6,7-dihydro-4-[(3-methylphenoxy)methyl]thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:1); RU-SKI 43 (hydrochloride)

物化性质

• 分子式: C₂₂H₃₁ClN₂O₂S
• 分子量: 423.012
• 精确质量: 422.179474
• 储存条件: -20°C，密闭，干燥