RU-SKI43 HCl
Modify Date: 2025-11-25 16:56:15
RU-SKI43 HCl structure
|
Common Name | RU-SKI43 HCl | ||
|---|---|---|---|---|
| CAS Number | 1782573-67-4 | Molecular Weight | 423.012 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H31ClN2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RU-SKI43 HClRU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR. |
| Name | RU-SKI 43 (hydrochloride) |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C22H31ClN2O2S |
|---|---|
| Molecular Weight | 423.012 |
| Exact Mass | 422.179474 |
| InChIKey | JBBKLHJLHRGJSQ-UHFFFAOYSA-N |
| SMILES | CCC(C)CNCC(=O)N1CCc2sccc2C1COc1cccc(C)c1.Cl |
| 2-[(2-Methylbutyl)amino]-1-{4-[(3-methylphenoxy)methyl]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl}ethanone hydrochloride (1:1) |
| MFCD25371547 |
| Ethanone, 1-[6,7-dihydro-4-[(3-methylphenoxy)methyl]thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:1) |
| RU-SKI 43 (hydrochloride) |