RU-SKI43 HCl结构式
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常用名 | RU-SKI43 HCl | 英文名 | RU-SKI43 HCl |
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CAS号 | 1782573-67-4 | 分子量 | 423.012 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C22H31ClN2O2S | 熔点 | N/A | |
MSDS | N/A | 闪点 | N/A |
RU-SKI43 HCl用途RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR. |
英文名 | RU-SKI 43 (hydrochloride) |
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英文别名 | 更多 |
分子式 | C22H31ClN2O2S |
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分子量 | 423.012 |
精确质量 | 422.179474 |
储存条件 | -20°C,密闭,干燥 |
2-[(2-Methylbutyl)amino]-1-{4-[(3-methylphenoxy)methyl]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl}ethanone hydrochloride (1:1) |
MFCD25371547 |
Ethanone, 1-[6,7-dihydro-4-[(3-methylphenoxy)methyl]thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:1) |
RU-SKI 43 (hydrochloride) |