1236-09-5

• 常用中文名：Pregn-5-ene-3,20-dione(6CI,7CI,8CI,9CI)
• 常用英文名：Pregn-5-ene-3,20-dione(6CI,7CI,8CI,9CI)
• CAS号：1236-09-5
• 分子式：C₂₁H₃₀O₂
• 分子量：314.46200
• 发布时间：2016-07-13 14:44:54
• 更新时间：2024-01-08 21:35:40

名称

• 英文名: pregn-5-ene-3,20-dione
• 英文别名: Pregn-5-en-3,20-dion; 5-Pregnene-3,20-dione; Pregn-5-ene-3,20-dione; isoprogesterone; (8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

物化性质

• 密度: 1.08g/cm3
• 沸点: 440.1ºC at 760mmHg
• 分子式: C₂₁H₃₀O₂
• 分子量: 314.46200
• 闪点: 164.2ºC
• 精确质量: 314.22500
• PSA: 34.14000
• LogP: 4.72350
• 蒸汽压: 6.03E-08mmHg at 25°C
• 折射率: 1.542

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU5002000 CHEMICAL NAME : Pregn-5-ene-3,20-dione CAS REGISTRY NUMBER : 1236-09-5 BEILSTEIN REFERENCE NO. : 3102499 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H30-O2 MOLECULAR WEIGHT : 314.51 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral DOSE : 35 mg/kg SEX/DURATION : female 7 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : JEMEAV Journal of Experimental Medicine. (Rockefeller Univ. Press, 1230 York Ave., New York, NY 10021) V.1- 1896- Volume(issue)/page/year: 102,347,1955

合成路线

145-13-1 ~75% 1236-09-5

文献：Bhati, Nishi; Sarma, Kuladip; Goswami, Amrit Synthetic Communications, 2008 , vol. 38, # 9 p. 1416 - 1424

38372-24-6 ~96% 1236-09-5

文献：Bortolini, O.; Campestrini, S.; Furia, F. Di; Modena, G.; Valle, G. Journal of Organic Chemistry, 1987 , vol. 52, # 24 p. 5467 - 5469

57-83-0 ~77% 1236-09-5

文献：D'Incan, E.; Viout, P. Tetrahedron, 1984 , vol. 40, # 18 p. 3421 - 3424

145-13-1 ~2% 2243-08-5 1236-09-5 604-19-3

文献：Solaja, Bogdan A.; Mili, Dragana R.; Do, Ljiljana I. Steroids, 1994 , vol. 59, # 5 p. 330 - 334

145-13-1 ~15% 2243-08-5 1236-09-5

文献：Acosta, C. Kirk; Rao, Pemmaraju N.; Kim, Hyun K. Steroids, 1993 , vol. 58, # 5 p. 205 - 208

58462-92-3 ~% 1236-09-5

文献：Freerksen, Robert W.; Selikson, Sandra J.; Wroble, Randall R.; Kyler, S. Keith; Watt, David S. Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4087 - 4096

145-13-1 ~% 57-83-0 1236-09-5

文献：Herl, Vanessa; Frankenstein, Joerdis; Meitinger, Nadine; Mueller-Uri, Frieder; Kreis, Wolfgang Planta Medica, 2007 , vol. 73, # 7 p. 704 - 710

805-33-4 ~% 1236-09-5

文献：Bucourt,R.; Dube,J. Bulletin de la Societe Chimique de France, 1974 , p. 479 - 483

上下游产品

上游产品  3
145-13-1 57-83-0 58462-92-3
下游产品  4
57-83-0 968-93-4 145-13-1 19037-28-6