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顺苯磺阿曲库铵

顺苯磺阿曲库铵用途

Cisatracurium苯磺酸盐是非去极化神经肌肉阻断剂,能通过抑制神经肌肉的传递拮抗乙酰胆碱的效用。

顺苯磺阿曲库铵名称

[ CAS 号 ]:
96946-42-8

[ 中文名 ]:
苯磺顺阿曲库胺

[ 英文名 ]:
Cisatracurium Besylate

[中文别名 ]:

[英文别名 ]:

Cisatracurium
Cis-AttacuriuM
(1R-cis,1'R-cis)-Atracurium besylate
cisatracurium besilate
Cisatracurium (besylate)
Cisatrcurium Besylate
UNII:Y78PS7MEDE
Cisatracurium besyla
Cisatracurium besylate (USAN)
Cisatracurium Besylate

顺苯磺阿曲库铵生物活性

[ 描述 ]:

Cisatracurium苯磺酸盐是非去极化神经肌肉阻断剂,能通过抑制神经肌肉的传递拮抗乙酰胆碱的效用。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 跨膜转运 >> 胆碱受体

信号通路 >> 神经信号通路 >> 胆碱受体

研究领域 >> 神经疾病

[参考文献]

[1]. Dear, G.J., et al., Identification of urinary and biliary conjugated metabolites of the neuromuscular blocker 51W89 by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom, 1995. 9(14): p. 1457-64.

[2]. Serra, C.S. and A.C. Oliveira, Cisatracurium: myographical and electrophysiological studies in the isolated rat muscle. Fundam Clin Pharmacol, 2006. 20(3): p. 291-8.

[相关活性小分子]

顺苯磺阿曲库铵物理化学性质

[ 熔点 ]:
90-93ºC

[ 分子式 ]:
C₆₅H₈₂N₂O₁₈S₂

[ 分子量 ]:
1243.479

[ 精确质量 ]:
1242.500366

[ PSA ]:
257.60000

[ LogP ]:
11.32610

[ 外观性状 ]:
白色粉末

[ 储存条件 ]:
室温，干燥

顺苯磺阿曲库铵安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H319

[ 警示性声明 ]:
Missing Phrase - N15.00950417-P305 + P351 + P338

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ 海关编码 ]:
2914509090

顺苯磺阿曲库铵海关

[ 海关编码 ]: 2914509090

[ 中文概述 ]:
2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

顺苯磺阿曲库铵文献

The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

Anesthesiology 82 , 1139-1145, (1995)

Atracurium is a mixture of ten stereoisomers. 51W89, one of these isomers, is a potent nondepolarizing intermediate-duration neuromuscular blocking agent. Preclinical studies have shown 51W89 to be si...

The cardiovascular effects and histamine-releasing properties of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

Anesthesiology 82 , 1131-1138, (1995)

Atracurium consists of a mixture of ten stereoisomers. One of these isomers, 51W89, is a potent intermediate-acting nondepolarizing neuromuscular blocking agent. Its ED95 is 0.05 mg.kg-1 in patients r...

Therapeutic efficacy of human mesenchymal stromal cells in the repair of established ventilator-induced lung injury in the rat.

Anesthesiology 122(2) , 363-73, (2015)

Rodent mesenchymal stem/stromal cells (MSCs) enhance repair after ventilator-induced lung injury (VILI). We wished to determine the therapeutic potential of human MSCs (hMSCs) in repairing the rodent ...

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