顺苯磺阿曲库铵

更新时间：2024-01-02 22:06:27

顺苯磺阿曲库铵结构式	常用名	顺苯磺阿曲库铵	英文名	Cisatracurium Besylate
	CAS号	96946-42-8	分子量	1243.479
	密度	N/A	沸点	N/A
	分子式	C₆₅H₈₂N₂O₁₈S₂	熔点	90-93ºC
	MSDS	中文版美版	闪点	N/A
	符号	GHS06	信号词	Danger

顺苯磺阿曲库铵用途

Cisatracurium苯磺酸盐是非去极化神经肌肉阻断剂,能通过抑制神经肌肉的传递拮抗乙酰胆碱的效用。

中文名	苯磺顺阿曲库胺
英文名	cisatracurium besylate
中文别名	顺苯磺阿曲库铵 \| (1R,1'R,2R,2'R)-2,2'-[1,5-戊二基双[氧(3-氧-3,1-丙二基)]]双[1-(3,4-二甲氧基苯基)甲基]-1,2,3,4-四氢-6,7-二甲氧基-2-甲基异喹啉]二苯磺酸盐 \| 顺苯磺阿曲库铵(1R \| 顺苯阿曲库铵
英文别名	更多

描述	Cisatracurium苯磺酸盐是非去极化神经肌肉阻断剂,能通过抑制神经肌肉的传递拮抗乙酰胆碱的效用。
相关类别	信号通路 >> 自噬 >> 自噬信号通路 >> 跨膜转运 >> 胆碱受体信号通路 >> 神经信号通路 >> 胆碱受体研究领域 >> 神经疾病
参考文献	[1]. Dear, G.J., et al., Identification of urinary and biliary conjugated metabolites of the neuromuscular blocker 51W89 by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom, 1995. 9(14): p. 1457-64. [2]. Serra, C.S. and A.C. Oliveira, Cisatracurium: myographical and electrophysiological studies in the isolated rat muscle. Fundam Clin Pharmacol, 2006. 20(3): p. 291-8.

描述

Cisatracurium苯磺酸盐是非去极化神经肌肉阻断剂,能通过抑制神经肌肉的传递拮抗乙酰胆碱的效用。

相关类别

信号通路 >> 自噬 >> 自噬

信号通路 >> 跨膜转运 >> 胆碱受体

信号通路 >> 神经信号通路 >> 胆碱受体

研究领域 >> 神经疾病

参考文献

[1]. Dear, G.J., et al., Identification of urinary and biliary conjugated metabolites of the neuromuscular blocker 51W89 by liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom, 1995. 9(14): p. 1457-64.

[2]. Serra, C.S. and A.C. Oliveira, Cisatracurium: myographical and electrophysiological studies in the isolated rat muscle. Fundam Clin Pharmacol, 2006. 20(3): p. 291-8.

熔点	90-93ºC
分子式	C₆₅H₈₂N₂O₁₈S₂
分子量	1243.479
精确质量	1242.500366
PSA	257.60000
LogP	11.32610
外观性状	白色粉末
储存条件	室温，干燥

符号	GHS06
信号词	Danger
危害声明	H301-H319
警示性声明	Missing Phrase - N15.00950417-P305 + P351 + P338
危险品运输编码	UN 2811 6.1 / PGIII
海关编码	2914509090

海关编码	2914509090
中文概述	2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

Anesthesiology 82 , 1139-1145, (1995)

Atracurium is a mixture of ten stereoisomers. 51W89, one of these isomers, is a potent nondepolarizing intermediate-duration neuromuscular blocking agent. Preclinical studies have shown 51W89 to be si...

The cardiovascular effects and histamine-releasing properties of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

Anesthesiology 82 , 1131-1138, (1995)

Atracurium consists of a mixture of ten stereoisomers. One of these isomers, 51W89, is a potent intermediate-acting nondepolarizing neuromuscular blocking agent. Its ED95 is 0.05 mg.kg-1 in patients r...

Therapeutic efficacy of human mesenchymal stromal cells in the repair of established ventilator-induced lung injury in the rat.

Anesthesiology 122(2) , 363-73, (2015)

Rodent mesenchymal stem/stromal cells (MSCs) enhance repair after ventilator-induced lung injury (VILI). We wished to determine the therapeutic potential of human MSCs (hMSCs) in repairing the rodent ...

Cisatracurium

Cisatracurium bes (Cisatracuriumbesylate/Clotrimazole)

(1R,2R,1'R,2'R)-2,2'-{1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate

[1R-[1a,2a(1'R*,2'R*)]]-2,2'[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] Dibenzenesulfonate

bisbenzènesulfonate de (1R,2R,1'R,2'R)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-diméthoxybenzyl)-6,7-diméthoxy-2-méthyl-1,2,3,4-tétrahydroisoquinoléinium]

(1R,2R,1'R,2'R)-2,2'-{Pentan-1,5-diylbis[oxy(3-oxopropan-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisochinolinium]bisbenzolsulfonat

Isoquinolinium, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R,2R,1'R,2'R)- benzenesulfonate (1:2)

Cis-AttacuriuM

(1R-cis,1'R-cis)-Atracurium besylate

cisatracurium besilate

Cisatracurium (besylate)

Cisatrcurium Besylate

UNII:Y78PS7MEDE

Cisatracurium besyla

1R,1R'-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl) methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate

Cisatracurium besylate (USAN)

(1R,2R,1'R,2'R)-2,2'-{Pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate

Cisatracurium Besylate

(1R,1'R)-atracurium besylate

1 kg-1.5kg

isoquinolinium, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1R,2R,1'R,2'R)- bisbenzenesulfonate

(1R,1'R,2R,2'R)

Atracurium Impurity 1