醋酸亮丙瑞林
醋酸亮丙瑞林结构式
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常用名 | 醋酸亮丙瑞林 | 英文名 | (Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH acetate salt |
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| CAS号 | 74381-53-6 | 分子量 | 1269.450 | |
| 密度 | N/A | 沸点 | 1720.5ºC at 760 mmHg | |
| 分子式 | C61H88N16O14 | 熔点 | 150-155ºC | |
| MSDS | 美版 | 闪点 | 994.3ºC |
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Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Bioorg. Med. Chem. 18 , 2225-31, (2010) There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability wi... |
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
J. Med. Chem. 51 , 6740-51, (2008) The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives, and the theoretical pr... |
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Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug Metab. Dispos. 36 , 1385-405, (2008) We present herein a compilation and trend analysis of human i.v. pharmacokinetic data on 670 drugs representing, to our knowledge, the largest publicly available set of human clinical pharmacokinetic data. This data set provides the drug metabolism scientist ... |
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Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 306(9) , R627-35, (2014) How sex steroids modulate glucocorticoid feedback on the hypothalamic-pituitary-corticotrope (HPC) unit is controversial in humans. We postulated that testosterone (T) in men and estradiol (E2) in women govern unstressed cortisol-mediated negative feedback on... |
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Two different formulations with equivalent effect? Comparison of serum estradiol suppression with monthly goserelin and trimonthly leuprolide in breast cancer patients.
Med. Oncol. 30(1) , 354, (2013) Data comparing the efficacy of monthly and trimonthly formulations of LHRH agonists are lacking. The aim of this study was to compare the effects of monthly goserelin and trimonthly leuprolide on estradiol levels. A total of 79 early breast cancer patients re... |
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Novasure as a mechanical endometrial preparation agent in large uteri.
JSLS 16(4) , 537-41, (2012) We evaluated Novasure ablation as a mechanical endometrial preparation agent before Roller Ball endometrial ablation in lieu of GnRH agonists in large uteri.A retrospective chart review of 20 consecutive patients undergoing Novasure ablation for mechanical en... |
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Comprehensive management of diffuse leiomyomatosis in a patient with Alport syndrome.
P. R. Health Sci. J. 32(4) , 200-2, (2013) Alport syndrome with diffuse leiomyomatosis (ASDL) is a complex combination that doesn't have a specific course of treatment. In this case report, we present a 44-year-old woman with ASDL and detail her treatment. The patient presented at the emergency room (... |
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[A posteriori biological demonstration of the concept of hormone-radiotherapy combination in cancer of the prostate].
Bull. Cancer 100(5) , 415-6, (2013)
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Spontaneous reports of seizure in association with leuprolide (lupron depot), goserelin (zoladex implant), and naferelin (synarel nasal spray).
Obstet. Gynecol. 121(5) , 1107, (2013)
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A role for androgen reduction treatment in Kennedy disease?
Muscle Nerve 47(6) , 789, (2013)
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