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2-氨基异丁酸甲酯盐酸盐

2-氨基异丁酸甲酯盐酸盐结构式
2-氨基异丁酸甲酯盐酸盐结构式
品牌特惠专场
常用名 2-氨基异丁酸甲酯盐酸盐 英文名 H-Aib-OMe.HCl
CAS号 15028-41-8 分子量 153.61
密度 N/A 沸点 120.6ºC at 760mmHg
分子式 C5H12ClNO2 熔点 185°C
MSDS 中文版 美版 闪点 56.1ºC

An efficient and expedient method for the synthesis of 11C-labeled α-aminoisobutyric acid: a tumor imaging agent potentially useful for cancer diagnosis.

Bioorg. Med. Chem. Lett. 21 , 2437-2440, (2011)

We describe the synthesis of (11)C-labeled α-aminoisobutyric acid 2 from iodo[(11)C]methane and methyl N-(diphenylmethylen)-d,l-alaniate (5). The tetrabutylammonium fluoride (TBAF)-promoted α-[(11)C]methylation of sterically hindered analog 5 was a key step i...

Peptide sweeteners. 6. Structural studies on the C-terminal amino acid of L-aspartyl dipeptide sweeteners.

J. Med. Chem. 27 , 1663-1668, (1984)

Stereochemical and structural aspects of the variations in the C-terminal residue of L-aspartyl-L-phenylalanine methyl ester have been investigated. Novel configurational analogues such as L-aspartyl-D-alanine benzyl ester and L-aspartyl-D-alpha-aminobutyric ...

Characterization of glycine transport in cultured Müller glial cells from the retina.

Glia 26 , 273-279, (1999)

Rapid termination of the synaptic action of glutamate (Glu) and glycine (Gly) is achieved by uptake into the presynaptic terminal and glial cells. In the vertebrate CNS, Gly acts both as an inhibitory neurotransmitter and as a Glu modulator or coagonist at po...

Effects of exogenous excitatory amino acid neurotransmitters on blood-brain barrier disruption in focal cerebral ischemia.

Neurochem. Res. 34 , 1249-1254, (2009)

This study was performed to determine whether exogenous N-methyl-D: -aspartate (NMDA) or alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) would aggravate blood-brain barrier (BBB) disruption in focal cerebral ischemia in rats. Forty-five minut...