LESINURAD (RDEA-594)中间体
LESINURAD (RDEA-594)中间体结构式
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常用名 | LESINURAD (RDEA-594)中间体 | 英文名 | NQDI 1 |
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| CAS号 | 175026-96-7 | 分子量 | 319.311 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 581.4±50.0 °C at 760 mmHg | |
| 分子式 | C19H13NO4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 305.4±30.1 °C |
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S632A3, a new glutarimide antibiotic, suppresses lipopolysaccharide-induced pro-inflammatory responses via inhibiting the activation of glycogen synthase kinase 3β.
Exp. Cell Res. 318(20) , 2592-603, (2012) Inflammatory mediators including inducible nitric oxide (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) contribute to the course of a variety of inflammatory diseases. S632A3 is a new member of the glutarimide antibi... |
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An ASK1-p38 signalling pathway mediates hydrogen peroxide-induced toxicity in NG108-15 neuronal cells.
Neurosci. Lett. 549 , 163-7, (2013) Reactive oxygen species (ROS) are believed to be involved in many forms of neurodegeneration, including ischaemic infarct damage and Alzheimer's disease. Despite the known involvement of p38 and JNK MAP kinases in mediating apoptosis and cell death in a varie... |
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